Detailed structural analysis of lipids directly on tissue specimens using a MALDI-SpiralTOF-Reflectron TOF mass spectrometer.
Detailed structural analysis of lipids directly on tissue specimens using a MALDI-SpiralTOF-Reflectron TOF mass spectrometer.
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DOI:
10.1371/journal.pone.0037107
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发表时间:
2012
期刊:
影响因子:
3.7
通讯作者:
Toyoda M
中科院分区:
文献类型:
--
作者:
Shimma S;Kubo A;Satoh T;Toyoda M
Direct tissue analysis using a novel tandem time-of-flight (TOF-TOF) mass spectrometer is described. This system consists of a matrix-assisted laser desorption/ionization ion source, a spiral ion trajectory TOF mass spectrometer “SpiralTOF (STOF)”, a collision cell, and an offset parabolic reflectron (RTOF). The features of this system are high precursor ion selectivity due to a 17-m flight path length in STOF and elimination of post-source decay (PSD) ions. The acceleration energy is 20 keV, so that high-energy collision-induced dissociation (HE-CID) is possible. Elimination of PSD ions allows observation of the product ions inherent to the HE-CID process. By using this tandem TOF instrument, the product ion spectrum of lipids provided detailed structural information of fatty acid residues.
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影响因子:
4.3
作者:
Chen R;Li L
通讯作者:
Li L
影响因子:
2
作者:
Goodwin, Richard J. A.;Pitt, Andrew R.;Harrison, David;Weidt, Stefan K.;Langridge-Smith, Pat R. R.;Barrett, Michael P.;Mackay, C. Logan
通讯作者:
Mackay, C. Logan
影响因子:
4.3
作者:
Marsching, Christian;Eckhardt, Matthias;Hopf, Carsten
通讯作者:
Hopf, Carsten
DOI:
10.1007/978-1-60761-746-4_12
发表时间:
2010-01-01
期刊:
MASS SPECTROMETRY IMAGING: PRINCIPLES AND PROTOCOLS
影响因子:
--
作者:
Garrett, Timothy J.;Yost, Richard A.
通讯作者:
Yost, Richard A.
影响因子:
2
作者:
Belgacem, Omar;Bowdler, Andrew;Raptakis, Emmanuel
通讯作者:
Raptakis, Emmanuel