Profiles of soluble proteins in chemosensory organs of three members of the afro-tropical Anopheles gambiae complex.
Profiles of soluble proteins in chemosensory organs of three members of the afro-tropical Anopheles gambiae complex.
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DOI：
10.1016/j.cbd.2017.07.005
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发表时间：
2017-12
期刊：
影响因子：
--
通讯作者：
Della Torre A
中科院分区：
文献类型：
--
作者：
Iovinella I;Caputo B;Calzetta M;Zwiebel LJ;Dani FR;Della Torre A
在雌性蚊子中，寻找寄主、选择寄主和其他生殖行为都是由气味驱动的。非洲热带冈比亚按蚊复合体的物种表现出不同的宿主偏好，其作为人类疟疾媒介的效率存在显着差异。气味感知开始于化学感受器，其主要位于触角和下颚须中。利用最近完成的基因组测序工作的冈比亚按蚊复杂的物种，我们应用鸟枪蛋白质组学的特点，可溶性蛋白质的三个不同的物种的触角和下颚须：一个。coluzzii，安. arabiensis和安. quadriannulatus，表现出显着的差异，在嗜酸性行为蛋白质谱，特别是关注可溶性蛋白质参与嗅觉为基础的气味检测进行了比较。昆虫角质层蛋白的丰度在物种之间存在一些差异。此外，蛋白质属于Glucose S-转移酶和气味结合蛋白，其中后者已知直接参与气味识别，也是不同的三个物种之间，与An。coluzzii和安氏隐翅虫An. arabiensis与An. quadriannulatus..
In mosquitoes females, host-seeking, host-choice and other reproductive behaviours are driven by odorants. Species of the Afrotropical Anopheles gambiae complex display divergent host-preferences associated with significant differences in their efficiency as vectors of human malaria. Odorant perception starts in chemosensilla which are primarily housed in the antennae and maxillary palps. Taking advantage of recently completed genome sequencing efforts for species of the Anopheles gambiae complex, we applied shotgun proteomics to characterize the profile of soluble proteins of antennae and maxillary palps of three different species: An. coluzzii, An. arabiensis and An. quadriannulatus, showing remarkable differences in anthropophilic behaviour Protein profiles with particular focus on soluble proteins involved in the olfactory-based detection of odours were compared. Several differences between species were found in the abundance of Insect Cuticle proteins. Moreover, proteins belonging to Glutathione S-transferase and Odorant binding proteins, the latter of which known to be directly involved in odour recognition, are also different among the three species, with An. coluzzii and An. arabiensis being less different with respect to An. quadriannulatus..
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影响因子：
6.7
作者：
Habtewold T;Povelones M;Blagborough AM;Christophides GK
通讯作者：
Christophides GK
影响因子：
3.3
作者：
Manoharan M;Ng Fuk Chong M;Vaïtinadapoulé A;Frumence E;Sowdhamini R;Offmann B
通讯作者：
Offmann B
影响因子：
4.4
作者：
Cox, Juergen;Neuhauser, Nadin;Mann, Matthias
通讯作者：
Mann, Matthias
影响因子：
2.6
作者：
Bohbot, J.;Pitts, R. J.;Zwiebel, L. J.
通讯作者：
Zwiebel, L. J.
DOI：
10.1073/pnas.0601107103
发表时间：
2006-09-05
影响因子：
11.1
作者：
Kwon, Hyung-Wook;Lu, Tan;Zwiebel, Laurence J.
通讯作者：
Zwiebel, Laurence J.