Pain, functional limitations, and aging.
Pain, functional limitations, and aging.
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DOI：
10.1111/j.1532-5415.2009.02388.x
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发表时间：
2009-09
影响因子：
6.3
通讯作者：
Yelin E
中科院分区：
文献类型：
--
作者：
Covinsky KE;Lindquist K;Dunlop DD;Yelin E
研究从中年到老年的不同年龄段的功能限制与疼痛之间的关系。横断面研究。2004年健康和退休研究（HRS），一项对50岁及以上社区生活者的全国代表性研究。2004年HRS中有18，531名参与者。那些报告说他们经常被中度或重度疼痛困扰的参与者被定义为有明显的疼痛。对于四个功能域中的每一个，受试者根据其功能限制程度进行分类：移动性（能慢跑1英里，能走几个街区，能走一个街区，不能走一个街区），爬楼梯（能爬几段，能爬一段，不能爬一段），上肢任务（能够做3、2、1或0）和日常生活活动（ADL）功能（能够毫无困难地做，有困难但能够在没有帮助的情况下做，需要帮助）。24%的参与者有明显的疼痛。在所有四个领域中，疼痛的参与者比没有疼痛的参与者有更高的功能限制率。疼痛的参与者在功能限制程度方面与年龄2至3岁的参与者相似。例如，对于移动性，在50至59岁的无疼痛受试者中，37%能够慢跑1英里，91%能够步行几个街区，96%能够毫无困难地步行一个街区。相比之下，在50至59岁的疼痛受试者中，9%的人能够慢跑1英里，50%的人能够步行几个街区，69%的人能够毫无困难地步行一个街区。50 - 59岁疼痛受试者与80 - 89岁无疼痛受试者在活动受限方面相似，其中4%能够慢跑1英里，55%能够行走几个街区，72%能够毫无困难地行走一个街区。在调整了人口统计学特征、社会经济状况、共病状况、抑郁症、肥胖症和健康习惯后，在所有四项指标中，有显著疼痛的参与者发生功能限制的风险要高得多（活动能力的校正比值比（AOR）= 2.85，95%可信区间（CI）= 2.20-3.69，爬楼梯的AOR = 2.84，95% CI = 2.48-3.26;上肢任务的AOR = 3.96，95%CI = 3.43-4.58; ADL功能的AOR = 4.33; 95%CI = 3.71-5.06）。患有疼痛的受试者在更早的年龄就出现了与衰老相关的典型功能限制。
To examine the relationship between functional limitations and pain across a spectrum of age, ranging from mid life to advanced old age. Cross-sectional study. The 2004 Health and Retirement Study (HRS), a nationally representative study of community-living persons aged 50 and older. Eighteen thousand five hundred thirty-one participants in the 2004 HRS. Participants who reported that they were often troubled by pain that was moderate or severe most of the time were defined as having significant pain. For each of four functional domains, subjects were classified according to their degree of functional limitation: mobility (able to jog 1 mile, able to walk several blocks, able to walk one block, unable to walk one block), stair climbing (able to climb several flights, able to climb one flight, not able to climb a flight), upper extremity tasks (able to do 3, 2, 1, or 0), and activity of daily living (ADL) function (able to do without difficulty, had difficulty but able to do without help, need help). Twenty-four percent of participants had significant pain. Across all four domains, participants with pain had much higher rates of functional limitations than subjects without pain. Participants with pain were similar in terms of their degree of functional limitation to participants 2 to 3 decades older. For example, for mobility, of subjects aged 50 to 59 without pain, 37% were able to jog 1 mile, 91% were able to walk several blocks, and 96% were able to walk one block without difficulty. In contrast, of subjects aged 50 to 59 with pain, 9% were able to jog 1 mile, 50% were able to walk several blocks, and 69% were able to walk one block without difficulty. Subjects aged 50 to 59 with pain were similar in terms of mobility limitations to subjects aged 80 to 89 without pain, of whom 4% were able to jog 1 mile, 55% were able to walk several blocks, and 72% were able to walk one block without difficulty. After adjustment for demographic characteristics, socioeconomic status, comorbid conditions, depression, obesity, and health habits, across all four measures, participants with significant pain were at much higher risk for having functional limitations (adjusted odds ratio (AOR) = 2.85, 95% confidence interval (CI) = 2.20–3.69, for mobility; AOR = 2.84, 95% CI = 2.48–3.26, for stair climbing; AOR = 3.96, 95% CI = 3.43–4.58, for upper extremity tasks; and AOR = 4.33; 95% CI = 3.71–5.06, for ADL function). Subjects with pain develop the functional limitations classically associated with aging at much earlier ages.
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DOI：
10.1111/j.1532-5415.1997.tb00986.x
发表时间：
1997-01-01
影响因子：
6.3
作者：
Fried, LP;Guralnik, JM
通讯作者：
Guralnik, JM
DOI：
10.7326/0003-4819-139-5_part_2-200309021-00015
发表时间：
2003-09-02
影响因子：
39.2
作者：
Fries, JF
通讯作者：
Fries, JF
DOI：
10.1111/j.1532-5415.1994.tb04968.x
发表时间：
1994-05-01
影响因子：
6.3
作者：
ENSRUD, KE;NEVITT, MC;CUMMINGS, SR
通讯作者：
CUMMINGS, SR
影响因子：
120.7
作者：
TINETTI, ME;INOUYE, SK;DOUCETTE, JT
通讯作者：
DOUCETTE, JT
DOI：
10.1093/gerona/60.6.793
发表时间：
2005-06-01
影响因子：
5.1
作者：
Reid, MC;Williams, CS;Gill, TM
通讯作者：
Gill, TM