KG-COVID-19: A Framework to Produce Customized Knowledge Graphs for COVID-19 Response.
KG-COVID-19: A Framework to Produce Customized Knowledge Graphs for COVID-19 Response.
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DOI:
10.1016/j.patter.2020.100155
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发表时间:
2021-01-08
期刊:
影响因子:
--
通讯作者:
Mungall CJ
中科院分区:
文献类型:
--
作者:
Reese JT;Unni D;Callahan TJ;Cappelletti L;Ravanmehr V;Carbon S;Shefchek KA;Good BM;Balhoff JP;Fontana T;Blau H;Matentzoglu N;Harris NL;Munoz-Torres MC;Haendel MA;Robinson PN;Joachimiak MP;Mungall CJ
Integrated, up-to-date data about SARS-CoV-2 and COVID-19 is crucial for the ongoing response to the COVID-19 pandemic by the biomedical research community. While rich biological knowledge exists for SARS-CoV-2 and related viruses (SARS-CoV, MERS-CoV), integrating this knowledge is difficult and time-consuming, since much of it is in siloed databases or in textual format. Furthermore, the data required by the research community vary drastically for different tasks; the optimal data for a machine learning task, for example, is much different from the data used to populate a browsable user interface for clinicians. To address these challenges, we created KG-COVID-19, a flexible framework that ingests and integrates heterogeneous biomedical data to produce knowledge graphs (KGs), and applied it to create a KG for COVID-19 response. This KG framework also can be applied to other problems in which siloed biomedical data must be quickly integrated for different research applications, including future pandemics. KG-COVID-19 is a framework for producing customized COVID-19 knowledge graphs Our knowledge graph and framework is free, open-source, and FAIR KG-COVID-19 integrates a wide range of COVID-19-related data in an ontology-aware way Our KG has been applied to use cases including ML tasks, hypothesis-based querying An effective response to the COVID-19 pandemic relies on integration of many different types of data available about SARS-CoV-2 and related viruses. KG-COVID-19 is a framework for producing knowledge graphs that can be customized for downstream applications including machine learning tasks, hypothesis-based querying, and browsable user interface to enable researchers to explore COVID-19 data and discover relationships. An effective response to the COVID-19 pandemic relies on integration of many different types of data available about SARS-CoV-2 and related viruses. KG-COVID-19 is a framework for producing knowledge graphs that can be customized for downstream applications including machine learning tasks, hypothesis-based querying, and browsable user interface to enable researchers to explore COVID-19 data and discover relationships.
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2016-08
期刊:
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