Brain injury and neural stem cells.
Brain injury and neural stem cells.
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DOI：
10.4103/1673-5374.224361
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发表时间：
2018-01
影响因子：
6.1
通讯作者：
Agrawal DK
中科院分区：
文献类型：
--
作者：
Ludwig PE;Thankam FG;Patil AA;Chamczuk AJ;Agrawal DK
许多有可能治疗脑损伤的疗法已经被研究过。在过去的几十年里，很少有类型的细胞能像干细胞那样激发人们的兴趣和兴奋。干细胞的多能性和自我更新特性赋予它们在缺血或退行性疾病以及创伤中再生失去组织的能力。虽然干细胞还没有像人们曾经希望的那样在许多这样的情况下被证明是有效的，但它们已经证明了一些可以用于临床效益的效果。各种类型的干细胞具有相似的特征，但在来源方面存在很大差异；已经分化到一定程度的细胞，其分化潜能可能有限。干细胞可以帮助减少脑损伤后的病变大小和改善功能。
Many therapies with potential for treatment of brain injury have been investigated. Few types of cells have spurred as much interest and excitement as stem cells over the past few decades. The multipotentiality and self-renewing characteristics of stem cells confer upon them the capability to regenerate lost tissue in ischemic or degenerative conditions as well as trauma. While stem cells have not yet proven to be clinically effective in many such conditions as was once hoped, they have demonstrated some effects that could be manipulated for clinical benefit. The various types of stem cells have similar characteristics, and largely differ in terms of origin; those that have differentiated to some extent may exhibit limited capability in differentiation potential. Stem cells can aid in decreasing lesion size and improving function following brain injury.
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影响因子：
9.8
作者：
Barazzuol, Lara;Ju, Limei;Jeggo, Penny A.
通讯作者：
Jeggo, Penny A.
DOI：
10.1111/j.1365-2990.1985.tb00027.x
发表时间：
1985-01-01
影响因子：
5
作者：
ADAMS, JH;DOYLE, D;SAKAMOTO, T
通讯作者：
SAKAMOTO, T
影响因子：
11
作者：
BLUMBERGS, PC;JONES, NR;NORTH, JB
通讯作者：
NORTH, JB
影响因子：
50.3
作者：
Bachoo, RM;Maher, EA;DePinho, RA
通讯作者：
DePinho, RA
影响因子：
25
作者：
Alsina, B;Vu, T;Cohen-Cory, S
通讯作者：
Cohen-Cory, S