Wearable Peripheral Electrical Stimulation Devices for the Reduction of Essential Tremor: A Review.
Wearable Peripheral Electrical Stimulation Devices for the Reduction of Essential Tremor: A Review.
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DOI：
10.1109/access.2021.3084819
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Kouzani AZ
中科院分区：
文献类型：
--
作者：
Karamesinis A;Sillitoe RV;Kouzani AZ
原发性震颤是最常见的病理性震颤，在65岁以上人群中患病率为6.3%。这种疾病会干扰患者独立进行日常生活活动的能力，并且通过医疗和手术干预治疗往往不足或有禁忌。由于不舒服和缺乏判断力，机械矫形器尚未被患者广泛采用。在过去的30年里，外周电刺激一直被研究作为一种可能的治疗方法，用于那些没有发现其他治疗方案令人满意的患者，近年来可穿戴设备彻底改变了这种新兴的方法。在本文中，概述特发性震颤及其目前的医疗和手术治疗方案。在此之后，探讨了震颤检测，测量和表征方法，重点是可以纳入可穿戴设备的测量选项。然后，描述了新的特发性震颤的干预措施，详细回顾了开环和闭环外周电刺激方法。最后，讨论了针对特发性震颤的可穿戴闭环外围电刺激装置的需求、其实现方法以及文献中有待进一步研究的空白。
Essential tremor is the most common pathological tremor, with a prevalence of 6.3% in people over 65 years of age. This disorder interferes with a patient’s ability to carry out activities of daily living independently, and treatment with medical and surgical interventions is often insufficient or contraindicated. Mechanical orthoses have not been widely adopted by patients due to discomfort and lack of discretion. Over the past 30 years, peripheral electrical stimulation has been investigated as a possible treatment for patients who have not found other treatment options to be satisfactory, with wearable devices revolutionizing this emerging approach in recent years. In this paper, an overview of essential tremor and its current medical and surgical treatment options are presented. Following this, tremor detection, measurement and characterization methods are explored with a focus on the measurement options that can be incorporated into wearable devices. Then, novel interventions for essential tremor are described, with a detailed review of open and closed-loop peripheral electrical stimulation methods. Finally, discussion of the need for wearable closed-loop peripheral electrical stimulation devices for essential tremor, approaches in their implementation, and gaps in the literature for further research are presented.
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