A Comparison of the Unfolded Protein Response in Solid-State with Submerged Cultures of Aspergillus oryzae

A Comparison of the Unfolded Protein Response in Solid-State with Submerged Cultures of Aspergillus oryzae
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米曲霉固态与深层培养物中未折叠蛋白反应的比较

DOI:
10.1271/bbb.80146
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发表时间:
2008-11
影响因子:
1.6
通讯作者:
Pan, Li
Pan, Li
中科院分区:
工程技术4区
文献类型:
--
作者:
Ye, Lei;Pan, Li

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未折叠蛋白反应(unfolded protein response,UPR)是维持内质网功能稳态的一个调节系统。本文比较了固态培养和深层培养条件下黑曲霉UPR相关基因的表达水平。结果表明,固态培养中UPR机制的上调高于液体培养(热激或非应激条件)。这可能是文化条件变化的结果。
The unfolded protein response (UPR) is a regulatory system to maintain the homeostasis of ER functions. Here we report a comparison of express levels of UPR relevant genes in Aspergillus oryzae between solid-state and submerged cultivation. The results were that up-regulation of the UPR mechanism in solid-state culture was higher than in submerged culture (heat-shock or non-stress conditions). This might have been a result of changing culture conditions.
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