A description of the methods of the Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be (nuMoM2b).
A description of the methods of the Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be (nuMoM2b).
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DOI：
10.1016/j.ajog.2015.01.019
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发表时间：
2015-04
影响因子：
9.8
通讯作者：
Reddy, Uma M.
中科院分区：
文献类型：
--
作者：
Haas, David M.;Parker, Corette B.;Wing, Deborah A.;Parry, Samuel;Grobman, William A.;Mercer, Brian M.;Simhan, Hyagriv N.;Hoffman, Matthew K.;Silver, Robert M.;Wadhwa, Pathik;Iams, Jay D.;Koch, Matthew A.;Caritis, Steve N.;Wapner, Ronald J.;Esplin, Sean;Elovitz, Michal A.;Foroud, Tatiana;Peaceman, Alan M.;Saade, George R.;Willinger, Marian;Reddy, Uma M.
Nulliparous妊娠结局研究：监测准妈妈（nuMoM2b）的主要目的是确定母体特征，包括遗传、对妊娠的生理反应以及预测不良妊娠结局（APO）的环境因素。在怀孕的前三个月未生育的妇女被招募到一个观察性队列研究。参与者在怀孕期间和分娩时分别进行了三次研究访问。我们收集的数据来自门诊访谈、带回家的调查、临床测量、超声研究和图表摘要。采集、处理和储存产前研究访视时的母体生物标本（血清、血浆、尿液和宫颈阴道液）和分娩标本（胎盘、脐带、脐带血）。研究的主要结局定义为妊娠在37+0周之前结束。关键研究假设涉及自发性早产、先兆子痫和胎儿生长受限的APO。10，037名女性被招募参加这项研究。在这篇方法论文中报告了筛选时队列的基本特征。nuMoM2b队列研究方法和程序可以帮助研究人员规划未来的项目。
The primary aim of The Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b) is to determine maternal characteristics, including genetic, physiological response to pregnancy, and environmental factors that predict adverse pregnancy outcomes (APOs). Nulliparous women in the first trimester of pregnancy were recruited into an observational cohort study. Participants were seen at three study visits during pregnancy and again at delivery. We collected data from in-clinic interviews, take-home surveys, clinical measurements, ultrasound studies, and chart abstractions. Maternal biospecimens (serum, plasma, urine and cervico-vaginal fluid) at antepartum study visits and delivery specimens (placenta, umbilical cord, cord blood) were collected, processed, and stored. The primary outcome of the study was defined as pregnancy ending prior to 37+0 weeks gestation. Key study hypotheses involve APOs of spontaneous preterm birth, preeclampsia, and fetal growth restriction. 10,037 women were recruited to the study. Basic characteristics of the cohort at screening are reported in this Methods paper. The nuMoM2b cohort study methods and procedures presented can help investigators when planning future projects.
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影响因子：
9.8
作者：
Esplin MS;Merrell K;Goldenberg R;Lai Y;Iams JD;Mercer B;Spong CY;Miodovnik M;Simhan HN;van Dorsten P;Dombrowski M;Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
通讯作者：
Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network
影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
7.4
作者：
Connor, KM;Davidson, JRT
通讯作者：
Davidson, JRT
DOI：
10.1080/01674820802546220
发表时间：
2008-12
期刊：
Journal of psychosomatic obstetrics and gynaecology
影响因子：
--
作者：
DiPietro JA;Christensen AL;Costigan KA
通讯作者：
Costigan KA
影响因子：
9.8
作者：
Crispi, Fatima;Dominguez, Carmen;Gratacos, Eduard
通讯作者：
Gratacos, Eduard