Health-Related Quality of Life in Chronic Liver Diseases: A Strong Impact of Hand Grip Strength
Health-Related Quality of Life in Chronic Liver Diseases: A Strong Impact of Hand Grip Strength
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慢性肝病患者的健康相关生活质量：握力的强烈影响
DOI：
10.3390/jcm7120553
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发表时间：
2018
影响因子：
3.9
通讯作者：
S. Nishiguchi
中科院分区：
文献类型：
--
作者：
H. Nishikawa;H. Enomoto;Kazunori Yoh;Y. Iwata;Yoshiyuki Sakai;K. Kishino;Naoto Ikeda;Tomoyuki Takashima;Nobuhiro Aizawa;R. Takata;Kunihiro Hasegawa;N. Ishii;Yukihisa Yuri;Takashi Nishimura;H. Iijima;S. Nishiguchi
我们试图研究握力（HGS）和骨骼肌质量（SMM）对健康相关生活质量（H-QOL）的影响，通过36项健康调查简表（SF-36）问卷在慢性肝病（CLD，198名男性和191名女性）中进行评估。HGS降低的定义为男性HGS <26 kg，女性<18 kg。使用生物阻抗分析，SMM降低定义为男性SMM指数<7.0 kg/m2，女性SMM指数<5.7 kg/m2。比较了按HGS或SMM分层的两组之间的SF-36评分。身体功能（PF）、身体角色（RP）、身体疼痛、活力（VT）、社会功能（SF）、情感角色（RE）和身体成分总分（PCS）项目的组间差异（HGS降低与未降低的HGS）达到显著性，而PF、SF和RE项目的组间差异（SMM降低与未降低的HGS）有统计学意义。多变量分析显示，HGS与男性PF（p = 0.0031）、RP（p = 0.0185）和PCS（p = 0.0421）显著相关，与女性PF（p = 0.0034）、VT（p = 0.0150）、RE（p = 0.0422）和PCS（p = 0.0191）显著相关。HGS对CLD的SF-36有很强的影响，尤其是在生理领域。
We sought to examine the influence of hand grip strength (HGS) and skeletal muscle mass (SMM) on the health-related quality of life (H-QOL) as evaluated by the 36-Item Short-Form Health Survey (SF-36) questionnaire in chronic liver diseases (CLDs, 198 men and 191 women). Decreased HGS was defined as HGS <26 kg for men and <18 kg for women. Decreased SMM was defined as SMM index <7.0 kg/m2 for men and <5.7 kg/m2 for women, using bioimpedance analysis. SF-36 scores were compared between groups stratified by HGS or SMM. Between-group differences (decreased HGS vs. non-decreased HGS) in the items of physical functioning (PF), role physical (RP), bodily pain, vitality (VT), social functioning (SF), role emotional (RE), and physical component summary score (PCS) reached significance, while between-group differences (decreased SMM vs. non-decreased SMM) in the items of PF, SF and RE were significant. Multivariate analyses revealed that HGS was significantly linked to PF (p = 0.0031), RP (p = 0.0185), and PCS (p = 0.0421) in males, and PF (p = 0.0034), VT (p = 0.0150), RE (p = 0.0422), and PCS (p = 0.0191) in females. HGS had a strong influence especially in the physiological domains in SF-36 in CLDs.
DOI：
10.1093/gerona/61.10.1059
发表时间：
2006-10-01
影响因子：
5.1
作者：
Goodpaster, Bret H.;Park, Seok Won;Newman, Anne B.
通讯作者：
Newman, Anne B.
DOI：
10.1007/978-3-319-70178-3_9
发表时间：
2017-01-01
期刊：
SEX AND GENDER FACTORS AFFECTING METABOLIC HOMEOSTASIS, DIABETES AND OBESITY
影响因子：
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作者：
Anderson, Lindsey J.;Liu, Haiming;Garcia, Jose M.
通讯作者：
Garcia, Jose M.