Validation of an Index for Functionally Important Respiratory Symptoms among Adults in the Nationally Representative Population Assessment of Tobacco and Health Study, 2014-2016.
Validation of an Index for Functionally Important Respiratory Symptoms among Adults in the Nationally Representative Population Assessment of Tobacco and Health Study, 2014-2016.
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DOI：
10.3390/ijerph18189688
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发表时间：
2021-09-14
影响因子：
--
通讯作者：
Brunette MF
中科院分区：
文献类型：
--
作者：
Halenar MJ;Sargent JD;Edwards KC;Woloshin S;Schwartz L;Emond J;Tanski S;Pierce JP;Taylor KA;Lauten K;Goniewicz ML;Niaura R;Anic G;Chen Y;Callahan-Lyon P;Gardner LD;Thekkudan T;Borek N;Kimmel HL;Cummings KM;Hyland A;Brunette MF
本研究的目的是验证来自国际儿童哮喘和过敏研究（ISAAC）的七项喘息模块，该模块在全国代表性的烟草与健康研究人群评估中。选择具有完整的第2-3波数据的成人参与者，包括哮喘患者，但不包括COPD和其他呼吸系统疾病患者（n = 16，295）。我们从ISAAC问题中创建了一个九点呼吸症状指数，评估了该指数的可靠性，并检查了与自我报告的哮喘诊断的相关性。评估阈值与功能结局的相关性。一种或多种呼吸道症状的加权患病率在无哮喘的成人中为18.0%（SE = 0.5），在终生哮喘的成人中为70.1%（SE = 1.3），在过去一年哮喘未服药的成人中为75.7%（SE = 3.7），在服药的成人中为92.6%（SE = 1.6）。呼吸道症状指数的Cronbach α为0.86。指数评分≥2或≥3时，功能重要的呼吸道症状患病率为7- 10%，识别哮喘的灵敏度和特异性足够，与所有功能结局和烟草使用变量的独立相关性一致。呼吸道症状指数评分≥2或≥3表示功能重要的呼吸道症状，可用于评估烟草使用与呼吸系统健康之间的关系。
The purpose of this study is to validate the seven-item wheezing module from the International Study of Asthma and Allergies in Children (ISAAC) in the nationally representative Population Assessment of Tobacco and Health Study. Adult participants with complete Wave 2–3 data were selected, including those with asthma but excluding those with COPD and other respiratory diseases (n = 16,295). We created a nine-point respiratory symptom index from the ISAAC questions, assessed the reliability of the index, and examined associations with self-reported asthma diagnosis. Threshold values were assessed for association with functional outcomes. The weighted prevalence for one or more respiratory symptom was 18.0% (SE = 0.5) for adults without asthma, 70.1% (SE = 1.3) for those with lifetime asthma, 75.7% (SE = 3.7) for adults with past-year asthma not on medications, and 92.6% (SE = 1.6) for those on medications. Cronbach’s alpha for the respiratory symptom index was 0.86. Index scores of ≥2 or ≥3 yielded functionally important respiratory symptom prevalence of 7–10%, adequate sensitivity and specificity for identifying asthma, and consistent independent associations with all functional outcomes and tobacco use variables. Respiratory symptom index scores of ≥2 or ≥3 are indicative of functionally important respiratory symptoms and could be used to assess the relationship between tobacco use and respiratory health.
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影响因子：
5.2
作者：
Hyland, Andrew;Ambrose, Bridget K.;Compton, Wilson M.
通讯作者：
Compton, Wilson M.
影响因子：
2.7
作者：
RIVEST, LP
通讯作者：
RIVEST, LP
影响因子：
24.3
作者：
Ellwood, Philippa;Asher, M. Innes;Strachan, David P.
通讯作者：
Strachan, David P.
验证Promis身体机能测量的癌症患者队列中各种各样的人群。
影响因子：
3.5
作者：
Jensen, Roxanne E.;Potosky, Arnold L.;Reeve, Bryce B.;Hahn, Elizabeth;Cella, David;Fries, James;Smith, Ashley Wilder;Keegan, Theresa H. M.;Wu, Xiao-Cheng;Paddock, Lisa;Moinpour, Carol M.
通讯作者：
Moinpour, Carol M.
影响因子：
24.3
作者：
ASHER, MI;KEIL, U;WILLIAMS, HC
通讯作者：
WILLIAMS, HC