Prevalence and factors associated with use of khat: a survey of patients entering HIV treatment programs in Ethiopia.

Prevalence and factors associated with use of khat: a survey of patients entering HIV treatment programs in Ethiopia.
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DOI:
10.1186/s13722-016-0069-2
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发表时间:
2017-01-06
影响因子:
3.7
通讯作者:
Slater L
Slater L
中科院分区:
医学2区
文献类型:
--
作者:
Lifson AR;Workneh S;Shenie T;Ayana DA;Melaku Z;Bezabih L;Waktola HT;Dagne B;Hilk R;Winters KC;Slater L

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阿拉伯茶是一种原产于东非的植物,含有类似苯丙胺的精神活性成分。长期使用阿拉伯茶可导致心理依赖,对身心健康造成多种损害,使艾滋病毒携带者的临床管理复杂化。在阿拉伯茶很常见的两个埃塞俄比亚城市,我们评估了新接触艾滋病毒治疗的患者使用阿拉伯茶的流行率和相关性。在2013-2014年间,我们调查了322名最近在德雷达瓦和哈拉尔的艾滋病毒诊所登记的患者,调查内容包括阿拉伯茶的使用、人口统计、吸烟和饮酒、临床疾病、食品不安全和社会支持。我们分析了过去一年中与阿拉伯茶使用相关的因素,以及最频繁使用阿拉伯茶的因素(基于典型月份使用的最大小时数)。242名(75%)受访者报告终生使用阿拉伯茶;209名(65%)报告在前一年使用阿拉伯茶。54%的阿拉伯茶使用者在19岁之前就开始了。尽管84%的人认为,如果你感染了艾滋病毒,每天使用阿拉伯茶对健康是危险的,但前一年使用阿拉伯茶的中位数为5小时/天和30天/月;21%的人表示,他们觉得有必要减少或控制阿拉伯茶的使用,但很难做到这一点。与不使用阿拉伯茶的人(分别为1%和31%)相比,使用阿拉伯茶的人报告吸烟(46%)和饮酒(49%)的可能性更大。那些报告使用最频繁的阿拉伯茶(≥180每小时/典型月)的人更有可能将自己的健康状况评为差,体重指数偏低(≤18.5公斤/平方米),报告更多的慢性病症状,并同意更多表明身体生活质量负面的说法。在多变量分析中,重度吸食者更有可能是男性、穆斯林和未婚人士。使用阿拉伯茶在进入护理的艾滋病毒患者中很常见,并与身体健康较差的症状有关。超过一半的人在年轻时就开始使用阿拉伯茶。尽管大多数人认为阿拉伯茶对艾滋病毒患者有害,但一些受访者报告说,他们在控制药物使用方面存在一些困难。在阿拉伯茶合法和广泛使用的环境中,制定负责任使用的干预措施是一项重要的健康优先事项,是对艾滋病毒携带者进行全面护理的一部分。
Khat, a plant native to East Africa, has psychoactive constituents similar to amphetamine. Chronic khat use can lead to psychological dependence with multiple physical and mental health harms, complicating clinical management of people living with HIV. In two Ethiopian cities where khat is common, we evaluated prevalence and correlates of khat use among patients new to HIV care. During 2013–2014, we surveyed 322 patients recently enrolled in HIV clinics in Dire Dawa and Harar about khat use, demographics, smoking and alcohol use, clinical illness, food insecurity, and social support. We analyzed factors associated with khat use in the past year, as well as heaviest use of khat (based on greatest number of hours used in a typical month). 242 (75%) respondents reported lifetime khat use; 209 (65%) reported khat use during the previous year. 54% of khat users started before age 19 years. Although 84% believed that using khat every day is dangerous for health if you have HIV, khat was used in the previous year a median of 5 h/days and 30 days/month; 21% said they felt a need to cut down or control their khat use but had difficulty doing so. Those using khat were more likely to report smoking (46%) and alcohol use (49%) compared to non-khat users (1 and 31% respectively). Those reporting heaviest khat use (≥180 h/typical month) were more likely to rate their health status as poor, have an underweight BMI (≤18.5 kg/m2), report more symptoms of chronic illness, and agree with more statements indicating a negative physical quality of life. In multivariate analysis, heavy users were more likely to be male, Muslim, and non-married. Khat use was common among HIV patients entering care, and associated with symptoms of poorer physical health. Over half started khat use when they were young. Although most believed khat is harmful for HIV patients, a number of respondents reported some difficulty controlling their drug use. In settings where khat is legal and widely utilized, developing interventions for responsible use represent an important health priority as part of comprehensive care for people living with HIV.
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