Discriminant Ability of the Eating Assessment Tool-10 to Detect Swallowing Safety and Efficiency Impairments.
Discriminant Ability of the Eating Assessment Tool-10 to Detect Swallowing Safety and Efficiency Impairments.
复制标题
DOI：
10.1002/lary.30043
复制
发表时间：
2022-12
期刊：
影响因子：
2.6
通讯作者：
Plowman, Emily K.
中科院分区：
文献类型：
--
作者：
Donohue, Cara;Gray, Lauren Tabor;Anderson, Amber;DiBiase, Lauren;Chapin, Jennifer;Wymer, James P.;Plowman, Emily K.
快速、灵敏的吞咽困难筛查工具对于识别高危患者至关重要，以便在繁忙的多学科肌萎缩侧索硬化症 (ALS) 诊所进行进一步评估。我们使用经过验证的饮食评估工具 10 (EAT-10) 来检查自我感知的吞咽困难与吞咽安全性和效率的视频荧光镜分析之间的关系。 ALS 患者完成了 EAT-10 和电视透视吞咽研究。对经过验证的吞咽毒性动态成像分级（DIGEST）量表进行重复、独立、盲法分析，以指数吞咽安全性和效率（轻度吞咽困难：DIGEST≥1，中度吞咽困难：DIGEST≥2）。进行组间方差分析和 Games-Howell 检验进行事后配对比较，以检查不同吞咽困难严重程度的 EAT-10 评分。得出接受者操作特征曲线分析、曲线下面积（AUC）、敏感性、特异性、阳性/阴性预测值（PPV、NPV）和比值比（OR）。分析了 435 个配对的 EAT-10 和 DIGEST 分数。平均 EAT-10 评分为 8.48（95% CI：7.63，9.33）。患有吞咽困难的个体表现出较高的 EAT-10 评分（轻度：4.1 vs. 11.3，中度：6.0 vs. 17.5，p<0.001）。平均 EAT-10 分数在消化水平上有所增加（D0：4.1，D1：7.9，D2：15.1，D3：20.4，D4：39.0）。对于轻度吞咽困难，最佳 EAT-10 切分为 3：AUC 0.74（95% CI：0.69-0.78；敏感性：77%；特异性：53%；PPV：71%；NPV：60%；OR：3.5）。中度吞咽困难的 EAT-10 削减分数为 7 优化检测：AUC 0.83（95% CI：0.78-0.87；敏感性：81%；特异性：66%；PPV：39%；NPV：93%；OR：8.1）。 EAT-10 是一种易于管理的吞咽困难筛查工具，具有良好的辨别能力，适用于 ALS 诊所。 2
Quick, sensitive dysphagia screening tools are necessary to identify high-risk patients for further evaluation in busy multidisciplinary amyotrophic lateral sclerosis (ALS) clinics. We examined the relationship between self-perceived dysphagia using the validated Eating Assessment Tool-10 (EAT-10) and videofluoroscopic analysis of swallowing safety and efficiency. Individuals with ALS completed the EAT-10 and a videofluoroscopic swallowing study. Duplicate, independent, blinded analyses of the validated Dynamic Imaging Grade of Swallowing Toxicity (DIGEST) scale were performed to index swallowing safety and efficiency (mild dysphagia: DIGEST≥1, moderate dysphagia: DIGEST≥2). A between groups ANOVA with Games-Howell test for post-hoc pairwise comparisons was performed to examine EAT-10 scores across dysphagia severity levels. Receiver operator characteristic curve analysis, area under the curve (AUC), sensitivity, specificity, positive/negative predictive values (PPV, NPV), and odds ratios (OR) were derived. 435 paired EAT-10 and DIGEST scores were analyzed. Mean EAT-10 score was 8.48 (95% CI: 7.63, 9.33). Individuals with dysphagia demonstrated higher EAT-10 scores (mild: 4.1 vs. 11.3, moderate: 6.0 vs. 17.5, p<0.001). Mean EAT-10 scores increased across DIGEST levels (D0: 4.1, D1:7.9, D2: 15.1, D3: 20.4, D4: 39.0). For mild dysphagia, an EAT-10 cut score of 3 was optimal: AUC 0.74 (95% CI: 0.69–0.78; sensitivity: 77%; specificity: 53%; PPV: 71%; NPV: 60%; OR: 3.5). An EAT-10 cut score of 7 optimized detection of moderate dysphagia: AUC 0.83 (95% CI: 0.78–0.87; sensitivity: 81%; specificity: 66%; PPV: 39%; NPV: 93%; OR: 8.1). The EAT-10 is an easy-to-administer dysphagia screening tool with good discriminant ability for use in ALS clinics. 2
登录
查看更多内容
影响因子：
3.4
作者：
Onesti E;Schettino I;Gori MC;Frasca V;Ceccanti M;Cambieri C;Ruoppolo G;Inghilleri M
通讯作者：
Inghilleri M
影响因子：
3.4
作者：
Chen, A;Garrett, CG
通讯作者：
Garrett, CG
影响因子：
2.9
作者：
Paris, G.;Martinaud, O.;Verin, E.
通讯作者：
Verin, E.
影响因子：
2.6
作者：
Nogueira, Dalia Santos;Ferreira, Pedro Lopes;Lopes, Ines Sousa
通讯作者：
Lopes, Ines Sousa
DOI：
10.3109/17482960802566824
发表时间：
2009-10
期刊：
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases
影响因子：
--
作者：
Chiò A;Logroscino G;Hardiman O;Swingler R;Mitchell D;Beghi E;Traynor BG;Eurals Consortium
通讯作者：
Eurals Consortium