Diversity in T cell memory: an embarrassment of riches.

Diversity in T cell memory: an embarrassment of riches.
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DOI:
10.1016/j.immuni.2009.11.007
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发表时间:
2009-12-18
期刊:
影响因子:
32.4
通讯作者:
Masopust D
Masopust D
中科院分区:
医学1区
文献类型:
--
作者:
Jameson SC;Masopust D

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The adaptive immune response meets the needs of the organism to generate effector cells capable of controlling pathogens, but also leads to production of memory cells, which mediate more effective protection during rechallenge. In this review we focus on the generation, maintenance and function of memory T cells, with a special emphasis on the increasing evidence for great diversity among functional memory T cell subsets.
抗原注射后进入排水淋巴结的CD4+ T细胞参与了主要反应并成为中央记忆细胞。
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