Leaf development: a cellular perspective.
Leaf development: a cellular perspective.
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DOI：
10.3389/fpls.2014.00362
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发表时间：
2014
影响因子：
5.6
通讯作者：
Beemster GT
中科院分区：
文献类型：
--
作者：
Kalve S;De Vos D;Beemster GT
通过其光合作用能力，叶片为整个植物的生长提供了基础。为了提高作物的产量和对未来气候情景的抵抗力，重要的是要获得对叶片生长和发育以及遗传和环境因素对该过程的影响的机械理解。细胞既是叶子的基本组成部分，也是将遗传和环境信息整合到发育程序中的调控单位。因此，为了从根本上了解叶的发育，需要能够重建单个细胞（及其后代）从干细胞龛到其在成熟叶中的最终位置的发育途径。为了建立这样的理解的基础，我们回顾了目前的知识的空间和时间的调节机制上运行的细胞，有助于形成一片叶子。我们专注于控制退出干细胞的命运，叶的起始，极性，细胞质生长，细胞分裂，核内复制，分裂和扩张之间的过渡，扩张和分化的分子网络和细胞间信号分子，包括植物激素，糖，肽，蛋白质和microRNAs的调节。我们讨论了在何种程度上的文献中提供的知识是适合应用于系统生物学方法来模拟叶片生长的过程中，为了更好地理解和预测叶片生长的模式物种拟南芥开始。
Through its photosynthetic capacity the leaf provides the basis for growth of the whole plant. In order to improve crops for higher productivity and resistance for future climate scenarios, it is important to obtain a mechanistic understanding of leaf growth and development and the effect of genetic and environmental factors on the process. Cells are both the basic building blocks of the leaf and the regulatory units that integrate genetic and environmental information into the developmental program. Therefore, to fundamentally understand leaf development, one needs to be able to reconstruct the developmental pathway of individual cells (and their progeny) from the stem cell niche to their final position in the mature leaf. To build the basis for such understanding, we review current knowledge on the spatial and temporal regulation mechanisms operating on cells, contributing to the formation of a leaf. We focus on the molecular networks that control exit from stem cell fate, leaf initiation, polarity, cytoplasmic growth, cell division, endoreduplication, transition between division and expansion, expansion and differentiation and their regulation by intercellular signaling molecules, including plant hormones, sugars, peptides, proteins, and microRNAs. We discuss to what extent the knowledge available in the literature is suitable to be applied in systems biology approaches to model the process of leaf growth, in order to better understand and predict leaf growth starting with the model species Arabidopsis thaliana.
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影响因子：
9.2
作者：
Achard, Patrick;Gusti, Andi;Genschik, Pascal
通讯作者：
Genschik, Pascal
影响因子：
7.4
作者：
Baima, S;Possenti, M;Morelli, G
通讯作者：
Morelli, G
影响因子：
3.7
作者：
Akita K;Hasezawa S;Higaki T
通讯作者：
Higaki T
影响因子：
7.4
作者：
Beemster, GTS;De Veylder, L;Vuylsteke, M
通讯作者：
Vuylsteke, M
DOI：
10.1038/nrm1663
发表时间：
2005-06
期刊：
Nature reviews. Molecular cell biology
影响因子：
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作者：
通讯作者：
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