Right ventricular function as assessed by cardiac magnetic resonance imaging-derived strain parameters compared to high-fidelity micromanometer catheter measurements.
Right ventricular function as assessed by cardiac magnetic resonance imaging-derived strain parameters compared to high-fidelity micromanometer catheter measurements.
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DOI：
10.1177/20458940211032529
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发表时间：
2021-10
影响因子：
2.6
通讯作者：
Hassoun PM
中科院分区：
文献类型：
--
作者：
Sato T;Ambale-Venkatesh B;Zimmerman SL;Tedford RJ;Hsu S;Chamera E;Fujii T;Mullin CJ;Mercurio V;Khair R;Corona-Villalobos CP;Simpson CE;Damico RL;Kolb TM;Mathai SC;Lima JAC;Kass DA;Tsujino I;Hassoun PM
右心功能对肺动脉高压患者的预后有重要意义。我们评估了心脏磁共振衍生的应变和应变率参数是否能可靠地反映毛细血管前肺动脉高压患者的右心室收缩和舒张功能。收缩末期弹性和右心室舒张时间常数τ，均来自有创高保真微压计导管测量，分别用作评估收缩和舒张右心室功能的金标准。连续19例毛细血管前肺动脉高压患者前瞻性地接受了心脏磁共振和右心导管检查。心脏磁共振数据与19名对照组进行了比较。在肺动脉高压患者中，评估了应变和应变率相关参数与有创血流动力学参数之间的相关性。PAH患者的纵向收缩期峰值应变、应变率和舒张早期应变率低于对照组;肺动脉高压患者的心房舒张期峰值应变率高于对照组。同样，肺动脉高压患者的环周收缩期峰值应变率较低，而心房舒张期峰值应变率较高。在肺动脉高压中，心脏磁共振和血流动力学测量的收缩期右心室功能之间不存在相关性。关于舒张期参数，tau与峰值纵向心房舒张期应变率（r =-0.61）、减速时间（r = 0.75）、纵向收缩期与舒张期时间比（r = 0.59）、舒张早期应变率（r =-0.5）、环周峰值心房舒张期应变率（r =-0.52）和减速时间（r = 0.62）显著相关。右心室舒张期应变分析是检测PAH患者右心室舒张功能障碍的可靠无创方法。
Right ventricular function has prognostic significance in patients with pulmonary hypertension. We evaluated whether cardiac magnetic resonance-derived strain and strain rate parameters could reliably reflect right ventricular systolic and diastolic function in precapillary pulmonary hypertension. End-systolic elastance and the time constant of right ventricular relaxation tau, both derived from invasive high-fidelity micromanometer catheter measurements, were used as gold standards for assessing systolic and diastolic right ventricular function, respectively. Nineteen consecutive precapillary pulmonary hypertension patients underwent cardiac magnetic resonance and right heart catheterization prospectively. Cardiac magnetic resonance data were compared with those of 19 control subjects. In pulmonary hypertension patients, associations between strain- and strain rate-related parameters and invasive hemodynamic parameters were evaluated. Longitudinal peak systolic strain, strain rate, and early diastolic strain rate were lower in PAH patients than in controls; peak atrial-diastolic strain rate was higher in pulmonary hypertension patients. Similarly, circumferential peak systolic strain rate was lower and peak atrial-diastolic strain rate was higher in pulmonary hypertension. In pulmonary hypertension, no correlations existed between cardiac magnetic resonance-derived and hemodynamically derived measures of systolic right ventricular function. Regarding diastolic parameters, tau was significantly correlated with peak longitudinal atrial-diastolic strain rate (r = −0.61), deceleration time (r = 0.75), longitudinal systolic to diastolic time ratio (r = 0.59), early diastolic strain rate (r = −0.5), circumferential peak atrial-diastolic strain rate (r = −0.52), and deceleration time (r = 0.62). Strain analysis of the right ventricular diastolic phase is a reliable non-invasive method for detecting right ventricular diastolic dysfunction in PAH.
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影响因子：
1.9
作者：
Mahran, Yossra;Schueler, Robert;Hammerstingl, Christoph
通讯作者：
Hammerstingl, Christoph
影响因子：
37.8
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Rain, Silvia;Handoko, M. Louis;de Man, Frances S.
通讯作者：
de Man, Frances S.
影响因子：
9.6
作者：
Sachdev, Arun;Villarraga, Hector R.;Kane, Garvan C.
通讯作者：
Kane, Garvan C.
影响因子：
2.8
作者：
Hardegree, Evan L.;Sachdev, Arun;Kane, Garvan C.
通讯作者：
Kane, Garvan C.
影响因子：
24
作者：
Opdahl, Anders;Venkatesh, Bharath Ambale;Fernandes, Veronica R. S.;Wu, Colin O.;Nasir, Khurram;Choi, Eui-Young;Almeida, Andre L. C.;Rosen, Boaz;Carvalho, Benilton;Edvardsen, Thor;Bluemke, David A.;Lima, Joao A. C.
通讯作者：
Lima, Joao A. C.