The concentration-response relation between PM(2.5) and daily deaths.
The concentration-response relation between PM(2.5) and daily deaths.
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PM(2.5) 与每日死亡人数之间的浓度-反应关系。
DOI：
10.1289/ehp.021101025
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发表时间：
2002-10
影响因子：
10.4
通讯作者：
Zanobetti A
中科院分区：
文献类型：
--
作者：
Schwartz J;Laden F;Zanobetti A
常见浓度的空气微粒污染与每日死亡人数有关。最近的注意力集中在浓度-反应曲线的形状上，特别是在低剂量下。最近的几篇文章报道，空气动力学直径<或= 10微米（PM(10)）的颗粒物与每日死亡有关，但没有证据表明存在一个阈值。这些报告在单个城市使用平滑或样条方法，并汇集多个城市的结果，以获得更稳健的估计。迄今为止，细颗粒物（空气动力学直径小于或等于2.5微米；PM(2.5)）， PM（10）的一个组成部分，尚未在这方面进行研究。我们在美国六个城市的分层模型中研究了这种联系。在第一阶段，我们拟合对数线性模型，包括每个城市PM（2.5）的平滑函数，控制季节，天气和一周中的一天。这些平滑函数允许城市特定关联中的非线性。我们使用允许异质性的分层模型将各城市的估计曲线结合起来。我们发现在2微克/米(3)以下基本呈线性关系。同样的方法被应用于检测对交通颗粒物的浓度响应，控制了来自其他来源的颗粒物。再一次，这种关联没有显示出阈值的迹象。这种关联的规模表明，控制细颗粒物污染将导致每年减少数千人的过早死亡。
Particulate air pollution at commonly occurring concentrations is associated with daily deaths. Recent attention has focused on the shape of the concentration-response curve, particularly at low doses. Several recent articles have reported that particulate matter with aerodynamic diameter < or = 10 microm (PM(10)) was associated with daily deaths with no evidence of a threshold. These reports have used smoothing or spline methods in individual cities and pooled the results across multiple cities to obtain estimates that are more robust. To date, fine particulate matter (aerodynamic diameter Less than or equal to 2.5 microm; PM(2.5)), a component of PM(10), has not been examined in this regard. We examined this association in a hierarchical model in six U.S. cities. In the first stage, we fit log-linear models including smooth functions of PM(2.5) in each city, controlling for season, weather, and day of the week. These smooth functions allowed for nonlinearities in the city-specific associations. We combined the estimated curves across cities using a hierarchical model that allows for heterogeneity. We found an essentially linear relationship down to 2 microg/m(3). The same approach was applied to examine the concentration response to traffic particles, controlling for particles from other sources. Once again, the association showed no sign of a threshold. The magnitude of the association suggests that controlling fine particle pollution would result in thousands of fewer early deaths per year.
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影响因子：
105.7
作者：
Katsouyanni, K;Touloumi, G;Anderson, HR
通讯作者：
Anderson, HR
影响因子：
2.1
作者：
POPE, CA;DOCKERY, DW;SCHWARTZ, J
通讯作者：
SCHWARTZ, J
影响因子：
8.3
作者：
SCHWARTZ, J
通讯作者：
SCHWARTZ, J
影响因子：
5.4
作者：
Schwartz, J;Neas, LM
通讯作者：
Neas, LM
DOI：
10.1093/biostatistics/1.3.279
发表时间：
2000-09-01
期刊：
Biostatistics (Oxford, England)
影响因子：
--
作者：
Zanobetti, A;Wand, M P;Ryan, L M
通讯作者：
Ryan, L M