Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials.
Extra Dose of Vitamin C Based on a Daily Supplementation Shortens the Common Cold: A Meta-Analysis of 9 Randomized Controlled Trials.
复制标题
DOI：
10.1155/2018/1837634
复制
发表时间：
2018
影响因子：
--
通讯作者：
Bu H
中科院分区：
文献类型：
--
作者：
Ran L;Zhao W;Wang J;Wang H;Zhao Y;Tseng Y;Bu H
研究维生素C对治疗普通感冒是否有效。 系统检索美国国家医学图书馆（PubMed）、科克伦图书馆、Elsevier、中国知网（CNKI）、维普数据库、万方数据库，在RevMan 5.3软件中纳入9篇随机安慰剂对照试验，均为英文。 在对维生素C的评估中，发现在感冒发作时给予额外的治疗剂量，尽管常规补充，但有助于缩短其持续时间（平均差（MD）=-0.56，95%可信区间（CI）[-1.03，-0.10]，P = 0.02），缩短室内禁闭时间（MD =-0.41，95%CI [-0.62，-0.19]，P = 0.0002），并缓解与之相关的症状，包括胸痛（MD =-0.40，95% CI [-0.77，-0.03]和P = 0.03），发热（MD =-0.45，95% CI [-0.78，-0.11]和P = 0.009）和寒战（MD =-0.36，95% CI [-0.65，-0.07]和P = 0.01）。 额外剂量的维生素C可以使一些尽管每天服用维生素C补充剂但仍患有普通感冒的患者受益。
To investigate whether vitamin C is effective in the treatment of the common cold. After systematically searching the National Library of Medicine (PubMed), Cochrane Library, Elsevier, China National Knowledge Infrastructure (CNKI), VIP databases, and WANFANG databases, 9 randomized placebo-controlled trials were included in our meta-analysis in RevMan 5.3 software, all of which were in English. In the evaluation of vitamin C, administration of extra therapeutic doses at the onset of cold despite routine supplementation was found to help reduce its duration (mean difference (MD) = -0.56, 95% confidence interval (CI) [-1.03, -0.10], and P = 0.02), shorten the time of confinement indoors (MD = -0.41, 95% CI [-0.62, -0.19], and P = 0.0002), and relieve the symptoms associated with it, including chest pain (MD = -0.40, 95% CI [-0.77, -0.03], and P = 0.03), fever (MD = -0.45, 95% CI [-0.78, -0.11], and P = 0.009), and chills (MD = -0.36, 95% CI [-0.65, -0.07], and P = 0.01). Extra doses of vitamin C could benefit some patients who contract the common cold despite taking daily vitamin C supplements.
登录
查看更多内容
影响因子：
4
作者：
Hozo SP;Djulbegovic B;Hozo I
通讯作者：
Hozo I
影响因子：
4.7
作者：
Hemilä, H
通讯作者：
Hemilä, H
影响因子：
158.5
作者：
COHEN, S;TYRRELL, DAJ;SMITH, AP
通讯作者：
SMITH, AP
影响因子：
6.2
作者：
Hicks, KL;Chemaly, RF;Kontoyiannis, DP
通讯作者：
Kontoyiannis, DP
影响因子：
11.4
作者：
Audera, C;Patulny, RV;Douglas, RM
通讯作者：
Douglas, RM