Vasopressin antagonists for patients with acute heart failure: interpreting new clinical and translational data.
Vasopressin antagonists for patients with acute heart failure: interpreting new clinical and translational data.
复制标题
加压素拮抗剂治疗急性心力衰竭患者:解释新的临床和转化数据。
DOI:
10.1038/clpt.2013.240
复制
发表时间:
2014
影响因子:
6.7
通讯作者:
Cheung,JY
中科院分区:
文献类型:
--
作者:
Feldman,AM;Hamad,E;Tsai,EJ;Zhu,W;Tilley,DG;Alvarez,R;Cheung,JY
Elevated levels of arginine vasopressin (AVP) are associated with a worse prognosis and the development of hyponatremia in patients with heart failure (HF). This observation led to the development of AVP receptor antagonists for the treatment of HF patients. Although AVP receptor antagonists increase serum sodium, their overall benefits in patients with HF have been at best modest, and recent data raise concerns about their safety in patients with acute HF and low serum sodium.
DOI:
10.1101/087969155.14.85
发表时间:
1982
期刊:
Cold Spring Harbor Monograph Archive
影响因子:
--
作者:
T. Bickle
通讯作者:
T. Bickle
影响因子:
2.9
作者:
HUBSCHER, U;PEDRALINOY, G;SPADARI, S
通讯作者:
SPADARI, S