Cross-sectional study on the proportion of smell and taste disturbances in hospitalized COVID-19 patients.
Cross-sectional study on the proportion of smell and taste disturbances in hospitalized COVID-19 patients.
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DOI：
10.1016/j.amsu.2021.102909
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发表时间：
2021-11
期刊：
影响因子：
--
通讯作者：
Yosia M
中科院分区：
文献类型：
--
作者：
Poerbonegoro NL;Reksodiputro MH;Sari DP;Mufida T;Rahman MA;Reksodiputro LA;Audindra S;Yosia M
The number of confirmed Coronavirus Disease-2019 (COVID-19) cases in Indonesia had reached 1.4 million cases from a total population of 270 million. Smell and/or taste disturbances are frequently found as early symptoms of COVID-19 patients. Our study aimed to investigate the proportion and characteristics of anosmia and/or ageusia in COVID-19. This cross-sectional study identifies the proportion and severity of smell and taste disturbances in COVID-19 patients. Subjects were recruited by consecutive sampling. All subjects were required to fill in the questionnaire modified from the American Academy of Otolaryngology-Head and Neck Surgery Anosmia Reporting Tool (AAO-HNS ART). Symptoms severity was measured with a numerical rating scale of 0–10; 0–3 is defined as mild, 4–6 as moderate, and 7–10 as severe. Out of 51 subjects, 34 (66.7%) suffered from smell and/or taste disturbances. Twenty-nine of 34 subjects (85.3%) suffered from smell disturbance, and 24 of 34 subjects (70.5%) suffered from taste disturbance. Severe smell disturbance occurred in 68.9% of subjects, while severe taste disturbance occurred in 50%. The median onset was three days for smell disturbance and four days for taste disturbance after any symptoms of COVID-19. Smell and/or taste disturbances were early symptoms of COVID-19. These symptoms commonly occurred within the first four days of clinical onset and frequently manifested in severe conditions. Studies shows that anosmia and ageusia are frequently found in COVID-19 patients. This study aimed at investigating occurrence of anosmia or ageusia in COVID-19. Out of 51 subjects observed, 34 (66.7%) suffered from anosmia and/or ageusia. Anosmia and ageusia commonly occurred within four days of COVID-19 symptoms onset.
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