Recent Development of Inorganic Nanoparticles for Biomedical Imaging.
Recent Development of Inorganic Nanoparticles for Biomedical Imaging.
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DOI：
10.1021/acscentsci.7b00574
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发表时间：
2018-03-28
影响因子：
18.2
通讯作者：
Hyeon T
中科院分区：
文献类型：
--
作者：
Kim D;Kim J;Park YI;Lee N;Hyeon T
基于无机纳米颗粒的生物医学成像探针作为传统分子成像探针的潜在替代品已被广泛研究。它们不仅可以提供更好的成像性能，还可以提供更广泛的多模式、刺激响应和靶向成像的多功能性。然而，由于安全问题和效率优化欠佳，基于无机纳米颗粒的探针距离临床实际使用还很遥远。在这种情况下，审视根本问题是很有价值的。这一前景凸显了用于 MRI、CT 和基于反斯托克斯位移的光学成像的无机纳米颗粒探针的最新进展。讨论了有关成像探头构造的各种问题和可能性，并提出了未来的研究方向。这一前景凸显了用于 MRI、CT 和基于反斯托克斯位移的光学成像的无机纳米颗粒探针的最新进展。
Inorganic nanoparticle-based biomedical imaging probes have been studied extensively as a potential alternative to conventional molecular imaging probes. Not only can they provide better imaging performance but they can also offer greater versatility of multimodal, stimuli-responsive, and targeted imaging. However, inorganic nanoparticle-based probes are still far from practical use in clinics due to safety concerns and less-optimized efficiency. In this context, it would be valuable to look over the underlying issues. This outlook highlights the recent advances in the development of inorganic nanoparticle-based probes for MRI, CT, and anti-Stokes shift-based optical imaging. Various issues and possibilities regarding the construction of imaging probes are discussed, and future research directions are suggested. This outlook highlights the recent advances in the development of inorganic nanoparticle-based probes for MRI, CT, and anti-Stokes shift-based optical imaging.
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影响因子：
10.8
作者：
Chen G;Damasco J;Qiu H;Shao W;Ohulchanskyy TY;Valiev RR;Wu X;Han G;Wang Y;Yang C;Ågren H;Prasad PN
通讯作者：
Prasad PN
影响因子：
13.3
作者：
Bansal, Akshaya;Liu, Haichun;Zhang, Yong
通讯作者：
Zhang, Yong
影响因子：
15
作者：
Bharali, DJ;Lucey, DW;Prasad, PN
通讯作者：
Prasad, PN
影响因子：
3.9
作者：
Cichy, B.;Wawrzynczyk, D.;Strek, W.
通讯作者：
Strek, W.
影响因子：
56.9
作者：
Bruchez, M;Moronne, M;Alivisatos, AP
通讯作者：
Alivisatos, AP