Global prevalence of autism: A systematic review update.
Global prevalence of autism: A systematic review update.
复制标题
DOI：
10.1002/aur.2696
复制
发表时间：
2022-05
期刊：
影响因子：
4.7
通讯作者：
Elsabbagh, Mayada
中科院分区：
文献类型：
--
作者：
Zeidan, Jinan;Fombonne, Eric;Scorah, Julie;Ibrahim, Alaa;Durkin, Maureen S.;Saxena, Shekhar;Yusuf, Afiqah;Shih, Andy;Elsabbagh, Mayada
自闭症患病率估计对于告知公共政策、提高认识和制定研究重点至关重要。通过系统回顾，我们综合了全球自闭症患病率的估计值。我们研究了导致估计变异的因素，并严格审查了与可能改变自闭症患病率估计的生物或社会决定因素（即生物性别、社会人口状况、民族/种族和出生地）假设相关的证据。我们于 2021 年 11 月在 Medline 内进行了搜索，以查找自 2012 年上次系统评价以来发表的估计自闭症患病率的研究。数据由两名独立研究人员提取。自 2012 年以来，发表了 71 项研究的 99 项估计值，表明全球自闭症患病率在区域内和区域间存在差异，患病率中位数为 100/10,000（范围：1.09/10,000 至 436.0/10,000）。男女比例中位数为 4.2。伴有智力障碍的自闭症病例的中位百分比为 33.0%。估计各不相同，可能反映了社区意识模式、服务能力、寻求帮助和社会人口因素之间复杂且动态的相互作用。本综述的一个局限性是综合方法学特征妨碍了研究的质量评估。我们的研究结果显示，全球范围内测得的自闭症患病率有所增加，反映了多种因素的综合影响，包括全球社区意识和公共卫生应对措施的提高、病例识别和定义的进展以及社区能力的提高。将增加患自闭症可能性的因素与患病率变化联系起来的假设需要随着时间的推移在世界不同地区进行大量、有代表性的样本和可比较的自闭症诊断标准和病例发现方法的研究。我们回顾了全球自闭症患病率的研究，考虑了地理、种族和社会经济因素对患病率估计的影响。全世界大约有 1/100 的儿童被诊断患有自闭症谱系障碍。患病率估计随着时间的推移而增加，并且在社会人口群体内部和之间差异很大。这些发现反映了自闭症定义的变化以及患病率研究方法和背景的差异。
Prevalence estimates of autism are essential for informing public policy, raising awareness, and developing research priorities. Using a systematic review, we synthesized estimates of the prevalence of autism worldwide. We examined factors accounting for variability in estimates and critically reviewed evidence relevant for hypotheses about biological or social determinants (viz., biological sex, sociodemographic status, ethnicity/race, and nativity) potentially modifying prevalence estimates of autism. We performed the search in November 2021 within Medline for studies estimating autism prevalence, published since our last systematic review in 2012. Data were extracted by two independent researchers. Since 2012, 99 estimates from 71 studies were published indicating a global autism prevalence that ranges within and across regions, with a median prevalence of 100/10,000 (range: 1.09/10,000 to 436.0/10,000). The median male‐to‐female ratio was 4.2. The median percentage of autism cases with co‐occurring intellectual disability was 33.0%. Estimates varied, likely reflecting complex and dynamic interactions between patterns of community awareness, service capacity, help seeking, and sociodemographic factors. A limitation of this review is that synthesizing methodological features precludes a quality appraisal of studies. Our findings reveal an increase in measured autism prevalence globally, reflecting the combined effects of multiple factors including the increase in community awareness and public health response globally, progress in case identification and definition, and an increase in community capacity. Hypotheses linking factors that increase the likelihood of developing autism with variations in prevalence will require research with large, representative samples and comparable autism diagnostic criteria and case‐finding methods in diverse world regions over time. We reviewed studies of the prevalence of autism worldwide, considering the impact of geographic, ethnic, and socioeconomic factors on prevalence estimates. Approximately 1/100 children are diagnosed with autism spectrum disorder around the world. Prevalence estimates increased over time and varied greatly within and across sociodemographic groups. These findings reflect changes in the definition of autism and differences in the methodology and contexts of prevalence studies.
登录
查看更多内容
影响因子：
1
作者：
Chinawa, Josephat M.;Manyike, Pius C.;Ibekwe, Roland R.
通讯作者：
Ibekwe, Roland R.
影响因子：
4.7
作者：
Beggiato, Anita;Peyre, Hugo;Delorme, Richard
通讯作者：
Delorme, Richard
影响因子：
3.7
作者：
Delobel-Ayoub M;Ehlinger V;Klapouszczak D;Maffre T;Raynaud JP;Delpierre C;Arnaud C
通讯作者：
Arnaud C
影响因子：
--
作者：
Al-Mamri, Watfa;Idris, Ahmed B;Islam, M Mazharul
通讯作者：
Islam, M Mazharul
DOI：
10.15585/mmwr.ss6513a1
发表时间：
2018-11-16
期刊：
Morbidity and mortality weekly report. Surveillance summaries (Washington, D.C. : 2002)
影响因子：
--
作者：
Christensen DL;Braun KVN;Baio J;Bilder D;Charles J;Constantino JN;Daniels J;Durkin MS;Fitzgerald RT;Kurzius-Spencer M;Lee LC;Pettygrove S;Robinson C;Schulz E;Wells C;Wingate MS;Zahorodny W;Yeargin-Allsopp M
通讯作者：
Yeargin-Allsopp M