A vision for a biomedical cloud.
A vision for a biomedical cloud.
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DOI:
10.1111/j.1365-2796.2011.02491.x
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发表时间:
2012-02
影响因子:
11.1
通讯作者:
White KP
中科院分区:
文献类型:
--
作者:
Grossman RL;White KP
We present a vision for a Systems Medicine Computing Cloud that draws on progress in the fields of Genomics, Systems Biology, and Biomedical Data Mining. The successful fusion of these areas will create a predictive matrix of biomarkers, genetic variants, and environmental variables that will drastically increase the specificity and timeliness of diagnosis for a wide range of common diseases, while delivering accurate predictions about the efficacy of treatment options. However, the amount of data being generated by each of these areas is staggering, as is the task of managing and analyzing it. Adequate computing infrastructure needs to be developed in order to assemble, manage, and mine the enormous and rapidly growing corpus of ‘omics’ data along with clinical information. We have now arrived at an intersection point between genome technology, cloud computing and biological data mining. This intersection point provides a launch pad for developing a globally applicable cloud computing platform capable of supporting a new paradigm of data intensive, cloud-enabled Systems Medicine.
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影响因子:
9.8
作者:
ENCODE Project Consortium
通讯作者:
ENCODE Project Consortium
影响因子:
9.9
作者:
Hua, Sujun;Kallen, Caleb B.;Dhar, Ruby;Baquero, Maria T.;Mason, Christopher E.;Russell, Beth A.;Shah, Parantu K.;Liu, Jiang;Khramtsov, Andrey;Tretiakova, Maria S.;Krausz, Thomas N.;Olopade, Olufunmilayo I.;Rimm, David L.;White, Kevin P.
通讯作者:
White, Kevin P.
DOI:
10.1126/science.1179050
发表时间:
2009-10-09
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Amit I;Garber M;Chevrier N;Leite AP;Donner Y;Eisenhaure T;Guttman M;Grenier JK;Li W;Zuk O;Schubert LA;Birditt B;Shay T;Goren A;Zhang X;Smith Z;Deering R;McDonald RC;Cabili M;Bernstein BE;Rinn JL;Meissner A;Root DE;Hacohen N;Regev A
通讯作者:
Regev A
影响因子:
30.8
作者:
Janssens, Hilde;Hou, Shuling;Reinitz, John
通讯作者:
Reinitz, John
DOI:
10.1073/pnas.0910200107
发表时间:
2010-04-06
影响因子:
11.1
作者:
McGary, Kriston L.;Park, Tae Joo;Marcotte, Edward M.
通讯作者:
Marcotte, Edward M.