Natural history of irritable bowel syndrome in women and dysmenorrhea: a 10-year follow-up study.

Natural history of irritable bowel syndrome in women and dysmenorrhea: a 10-year follow-up study.
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DOI:
10.1155/2012/534204
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发表时间:
2012
影响因子:
2
通讯作者:
Thjodleifsson B
Thjodleifsson B
中科院分区:
医学4区
文献类型:
--
作者:
Olafsdottir LB;Gudjonsson H;Jonsdottir HH;Björnsson E;Thjodleifsson B

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背景研究表明,女性更有可能患有肠易激综合征(IBS),更多的女性因为IBS而寻求医疗保健。瞄准我们想研究10年来女性IBS和痛经的自然史,并评估绝经后IBS的变化。法基于人口的邮政研究。1996年和2006年分别向冰岛18-75岁人口中相同年龄和性别分层的随机抽样人群邮寄了一份调查问卷。结果1996年,77%的绝经前妇女患有痛经,2006年为74%。根据曼宁标准,2006年42%的痛经妇女患有IBS,1996年为49%。根据2006年罗马III,26%的痛经女性患有IBS,1996年为11%。在2006年,30%的妇女有严重或非常严重的痛经。更多的妇女(27%)报告严重腹痛绝经后比绝经前11%。没有痛经的女性保持无症状的可能性是有痛经的女性的两倍。患有痛经的女性更可能有稳定的症状,并且症状增加的可能性是女性的两倍。结论患有IBS的女性比没有IBS的女性更容易经历痛经,这似乎是大多数患有IBS的女性的月经学的一部分。IBS症状的严重程度似乎在绝经后增加。
Background. Studies have shown that women are more likely to have irritable bowel syndrome (IBS) and more women seek healthcare because of IBS than men. Aim. We wanted to examine the natural history of IBS and dysmenorrhea in women over a 10-year period and to assess the change in IBS after menopause. Method. A population-based postal study. A questionnaire was mailed to the same age- and gender-stratified random sample of the Icelandic population aged 18–75 in 1996 and again in 2006. Results. 77% premenopausal women had dysmenorrhea in the year 1996 and 74% in 2006. 42% of women with dysmenorrhea had IBS according to Manning criteria in the year 2006 and 49% in 1996. 26% of women with dysmenorrhea had IBS according to Rome III 2006 and 11% in the year 1996. In 2006 30% women had severe or very severe dysmenorrhea pain severity. More women (27%) reported severe abdominal pain after menopause than before menopause 11%. Women without dysmenorrhea were twice more likely to remain asymptomatic than the women with dysmenorrhea. Women with dysmenorrhea were more likely to have stable symptoms and were twice more likely to have increased symptoms. Conclusion. Women with IBS are more likely to experience dysmenorrhea than women without IBS which seems to be a part of the symptomatology in most women with IBS. IBS symptom severity seems to increase after menopause.
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