Vitamin D status among adults in Germany--results from the German Health Interview and Examination Survey for Adults (DEGS1).
Vitamin D status among adults in Germany--results from the German Health Interview and Examination Survey for Adults (DEGS1).
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DOI：
10.1186/s12889-015-2016-7
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发表时间：
2015-07-11
影响因子：
4.5
通讯作者：
Mensink GB
中科院分区：
文献类型：
--
作者：
Rabenberg M;Scheidt-Nave C;Busch MA;Rieckmann N;Hintzpeter B;Mensink GB
1998年，德国超过一半的成年人血清25-羟基维生素D [25(OH)D]水平低于50 nmol/l的常见阈值。从那时起，维生素D在科学界、媒体和普通人群中引起了很多关注，血清25(OH)D水平可能因此而增加。根据“德国成人健康访谈和检查调查”（DEGS1）的数据，可以分析维生素D的现状。DEGS1是由罗伯特·科赫研究所在2008年至2011年期间对德国成年人进行的一项全国健康调查，包括6,995名血清25(OH)D水平可用的人。我们根据年龄、季节、居住纬度以及按检查月份计算血清25(OH)D百分位数，计算血清25(OH)D水平<30 nmol/l、30- < 50 nmol/l和> =50 nmol/l的参与者比例。用多元线性回归模型分析维生素D状态的决定因素。平均血清25(OH)D水平为45.6 nmol/l，性别差异无统计学意义（p = 0.47）。61.6%的受试者血清25(OH)D水平<50 nmol/l， 30.2%的受试者血清25(OH)D水平<30 nmol/l。在夏季，一半的参与者水平> =50 nmol/l，在冬季，25%的参与者水平<30 nmol/l。男性在秋季和女性在冬季存在显著的纬度梯度。在多元线性回归分析中，冬季检查、居住在北纬地区、不使用维生素D补充剂、低运动活动、高身体质量指数（BMI）和高媒体消耗与男女血清25(OH)D水平降低独立且显著相关。此外，在女性中，25(OH)D水平较低与年龄较大和社会经济地位较低有显著关联，而在男性中，维生素D摄入量低和住宅交通较多。血清25(OH)D水平低于50 nmol/l的阈值在德国成年人中仍然很常见，特别是在冬季和春季以及高纬度地区。较差的维生素D水平的潜在可改变因素是较高的身体质量指数，缺乏体育活动和高媒体使用。
In 1998, more than half of the adult population in Germany had serum 25-hydroxy-vitamin-D [25(OH)D] levels below the common threshold of 50 nmol/l. Since then, there has been a lot of attention for vitamin D in the scientific community, the media and the general population and serum 25(OH)D levels may have increased as a consequence. With data from the ‘German Health Interview and Examination Survey for Adults’ (DEGS1) the current situation of vitamin D status can be analysed. DEGS1, a national health survey among adults in Germany conducted by the Robert Koch Institute between 2008 and 2011, included 6,995 persons with available serum 25(OH)D levels. We calculated the proportion of participants with serum 25(OH)D levels <30 nmol/l, 30- < 50 nmol/l and > =50 nmol/l overall and according to age, season and latitude of residence as well as percentiles of serum 25(OH)D according to month of examination. Determinants of vitamin D status were analysed with multiple linear regression models. Mean serum 25(OH)D level was 45.6 nmol/l with no significant sex differences (p = 0.47). 61.6 % of the participants had serum 25(OH)D levels <50 nmol/l, 30.2 % had levels <30 nmol/l. During summer, half of the participants had levels > =50 nmol/l, during winter time, 25 % of the participants had levels <30 nmol/l. A significant latitudinal gradient was observed in autumn for men and in winter for women. In multiple linear regression analyses, examination during winter time, residing in northern latitude, non-use of vitamin D supplements, low sport activity, high Body Mass Index (BMI) and high media consumption were independently and significantly associated with lower serum 25(OH)D levels in both sexes. In addition, among women, significant associations with lower 25(OH)D levels were observed for older age and lower socio-economic status, among men, for low vitamin D intake and more residential traffic. Serum 25(OH)D levels below the threshold of 50 nmol/l are still common among adults in Germany, especially during winter and spring and in higher latitudes. Potentially modifiable factors of poorer vitamin D status are higher BMI, lack of sport activity and high media use.
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影响因子：
4.5
作者：
Forrest, Kimberly Y. Z.;Stuhldreher, Wendy L.
通讯作者：
Stuhldreher, Wendy L.
影响因子：
5.8
作者：
Gagnon, Claudia;Baillargeon, Jean-Patrice;Fink, Guy D.
通讯作者：
Fink, Guy D.
影响因子：
5.8
作者：
Holick, Michael F.;Binkley, Neil C.;Weaver, Connie M.
通讯作者：
Weaver, Connie M.
DOI：
10.4161/derm.20731
发表时间：
2012-04-01
期刊：
Dermato-endocrinology
影响因子：
--
作者：
Gröber U;Kisters K
通讯作者：
Kisters K
影响因子：
7.1
作者：
Cashman, Kevin D.;Kiely, Mairead;Sempos, Christopher T.
通讯作者：
Sempos, Christopher T.