Detection Technologies for Reactive Oxygen Species: Fluorescence and Electrochemical Methods and Their Applications.
Detection Technologies for Reactive Oxygen Species: Fluorescence and Electrochemical Methods and Their Applications.
复制标题
活性氧检测技术：荧光和电化学方法及其应用。
DOI：
10.3390/bios11020030
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发表时间：
2021-01-24
期刊：
影响因子：
--
通讯作者：
Kim DS
中科院分区：
文献类型：
--
作者：
Duanghathaipornsuk S;Farrell EJ;Alba-Rubio AC;Zelenay P;Kim DS
活性氧 (ROS) 已在植物、哺乳动物和自然环境过程中发现。哺乳动物中活性氧的存在与严重疾病的发生有关，例如糖尿病、癌症、肿瘤和几种神经退行性疾病。与人类健康相关的最常见的ROS是超氧化物、过氧化氢(H2O2)和羟基自由基(·OH)。有机和无机分子已与各种方法相结合来检测和监测ROS，以了解它们的存在和浓度对氧化应激引起的疾病的影响。在多种技术中，荧光和电化学方法最近被开发并用于检测 ROS。本文献综述旨在批判性地讨论迄今为止这些技术的发展，以及它们在自由基相关疾病的体外和体内 ROS 检测中的应用。此外，还介绍了使用荧光和电化学方法检测 ROS 的重要见解和进一步步骤。
Reactive oxygen species (ROS) have been found in plants, mammals, and natural environmental processes. The presence of ROS in mammals has been linked to the development of severe diseases, such as diabetes, cancer, tumors, and several neurodegenerative conditions. The most common ROS involved in human health are superoxide , hydrogen peroxide (H2O2), and hydroxyl radicals (•OH). Organic and inorganic molecules have been integrated with various methods to detect and monitor ROS for understanding the effect of their presence and concentration on diseases caused by oxidative stress. Among several techniques, fluorescence and electrochemical methods have been recently developed and employed for the detection of ROS. This literature review intends to critically discuss the development of these techniques to date, as well as their application for in vitro and in vivo ROS detection regarding free-radical-related diseases. Moreover, important insights into and further steps for using fluorescence and electrochemical methods in the detection of ROS are presented.
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影响因子：
4.2
作者：
Barbin, Luiz Eduardo;Saquy, Paulo Cesar;Pecora, Jesus Djalma
通讯作者：
Pecora, Jesus Djalma
DOI：
10.1073/pnas.88.19.8440
发表时间：
1991-10-01
影响因子：
11.1
作者：
BURKITT, MJ;MASON, RP
通讯作者：
MASON, RP
影响因子：
3
作者：
Blaskovicova, Jana;Sochr, Jozef;Labuda, Jan
通讯作者：
Labuda, Jan
影响因子：
3.2
作者：
Amatore, Christian;Arbault, Stephane;Koh, Alaric C. W.
通讯作者：
Koh, Alaric C. W.
影响因子：
2.7
作者：
Cao, Linying;Wu, Qingfeng;Guo, Yong
通讯作者：
Guo, Yong