Growth Hormone and IGF-I as Anabolic Partitioning Hormones
Growth Hormone and IGF-I as Anabolic Partitioning Hormones
复制标题
生长激素和 IGF-I 作为合成代谢分配激素
DOI:
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发表时间:
1995
期刊:
影响因子:
--
通讯作者:
D. Clemmons
中科院分区:
文献类型:
--
作者:
D. Clemmons
Growth hormone (GH) is an anabolic hormone that stimulates protein synthesis in normal volunteers. Although it also stimulates protein catabolism, the increase in protein synthesis is significantly greater than the concomitant increase in catabolism, resulting in net protein accretion. Two types of interventions have been used to induce catabolism in normal volunteers. These include caloric restriction and administration of glucocorticoids (1, 2). Normal volunteers who received high doses of prednisone to induce nitrogen loss responded to GH with significant improvement in nitrogen balance and an increase in nonoxidative leucine metabolism, which is an index of stimulation of protein synthesis (3). Similarly, several studies in calorically restricted normal volunteers have shown that GH results in protein conservation (4, 5).
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DOI:
10.1177/0148607190014006574
发表时间:
1990
期刊:
JPEN. Journal of parenteral and enteral nutrition
影响因子:
--
作者:
Ziegler,TR;Young,LS;Ferrari-Baliviera,E;Demling,RH;Wilmore,DW
通讯作者:
Wilmore,DW
DOI:
10.1210/jcem.75.1.1619015
发表时间:
1992
期刊:
The Journal of clinical endocrinology and metabolism
影响因子:
--
作者:
Clemmons,DR;Smith-Banks,A;Underwood,LE
通讯作者:
Underwood,LE
DOI:
10.1016/s0021-9258(18)67484-8
发表时间:
1986-08
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Charles T. Roberts;A. L. Brown;D. Graham;Steven Seelig;Susan A. Berry;K. Gabbay;M. Rechler
通讯作者:
Charles T. Roberts;A. L. Brown;D. Graham;Steven Seelig;Susan A. Berry;K. Gabbay;M. Rechler
DOI:
10.1210/jcem.77.4.8408471
发表时间:
1993
期刊:
The Journal of clinical endocrinology and metabolism
影响因子:
--
作者:
Mulligan,K;Grunfeld,C;Hellerstein,MK;Neese,RA;Schambelan,M
通讯作者:
Schambelan,M
影响因子:
15.9
作者:
HORBER, FF;HAYMOND, MW
通讯作者:
HAYMOND, MW