A review of decreased sound tolerance in autism: Definitions, phenomenology, and potential mechanisms.

A review of decreased sound tolerance in autism: Definitions, phenomenology, and potential mechanisms.
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自闭症声音耐受性下降的回顾:定义、现象学和潜在机制。

DOI:
10.1016/j.neubiorev.2020.11.030
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发表时间:
2021-03
影响因子:
8.2
通讯作者:
Woynaroski TG
Woynaroski TG
中科院分区:
医学1区
文献类型:
--
作者:
Williams ZJ;He JL;Cascio CJ;Woynaroski TG

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Atypical behavioral responses to environmental sounds are common in autistic children and adults, with 50–70% of this population exhibiting decreased sound tolerance (DST) at some point in their lives. This symptom is a source of significant distress and impairment across the lifespan, contributing to anxiety, challenging behaviors, reduced community participation, and school/workplace difficulties. However, relatively little is known about its phenomenology or neurocognitive underpinnings. The present article synthesizes a large body of literature on the phenomenology and pathophysiology of DST-related conditions to generate a comprehensive theoretical account of DST in autism. Notably, we argue against conceptualizing DST as a unified construct, suggesting that it be separated into three phenomenologically distinct conditions: hyperacusis (the perception of everyday sounds as excessively loud or painful), misophonia (an acquired aversive reaction to specific sounds), and phonophobia (a specific phobia of sound), each responsible for a portion of observed DST behaviors. We further elaborate our framework by proposing preliminary neurocognitive models of hyperacusis, misophonia, and phonophobia that incorporate neurophysiologic findings from studies of autism.
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期刊: Neuroscience
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