A small predatory core genome in the divergent marine Bacteriovorax marinus SJ and the terrestrial Bdellovibrio bacteriovorus.
A small predatory core genome in the divergent marine Bacteriovorax marinus SJ and the terrestrial Bdellovibrio bacteriovorus.
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DOI：
10.1038/ismej.2012.90
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发表时间：
2013-01
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影响因子：
--
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中科院分区：
文献类型：
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海洋食菌菌（Bacteriovorax marinus SJ）是从海洋环境中分离的一种捕食性δ-变形杆菌。该菌株的基因组序列与陆生捕食性细菌噬菌蛭弧菌HD 100的基因组序列形成了有趣的对比。基于它们的捕食性生活方式，Bacteriovorax最初被指定为蛭弧菌属的成员，但随后基于遗传和表型差异被重新分配到一个新的属和科。B。marinus附着在革兰氏阴性细菌上，穿透细胞壁形成原生质体，并在其中复制，如显微镜所示。噬菌菌是独特的，因为它与其最近的测序亲属只有30%的基因产物。值得注意的是，34%长度超过500 nt的预测基因是完全独特的，在数据库中没有显著的匹配。正如预期的那样，Bacteriovorax与其他δ-变形菌共有几个特征位点。在Bacteriovorax和蛭弧菌之间共享的基因组在其他δ-变形菌中不保守，例如粘细菌（其通过溶解作用从外部破坏猎物细菌），或非捕食性脱硫细菌和Geelovibrio物种被鉴定。这291个基因的直系同源共同Bacteriovorax和蛭弧菌可能是宿主相互作用的捕食者特定的过程所需的猎物进入的关键指标。噬菌蛭弧菌的基因座与从捕食性到猎物/宿主独立生长的转变有关。虽然该位点在B中是保守的。marinus，序列只有有限的相似性。这项研究的结果推进了对蛭弧菌和噬菌体之间的相似性和差异的理解，并证实了两者之间的遥远关系和它们分离到不同的家庭。
Bacteriovorax marinus SJ is a predatory delta-proteobacterium isolated from a marine environment. The genome sequence of this strain provides an interesting contrast to that of the terrestrial predatory bacterium Bdellovibrio bacteriovorus HD100. Based on their predatory lifestyle, Bacteriovorax were originally designated as members of the genus Bdellovibrio but subsequently were re-assigned to a new genus and family based on genetic and phenotypic differences. B. marinus attaches to Gram-negative bacteria, penetrates through the cell wall to form a bdelloplast, in which it replicates, as shown using microscopy. Bacteriovorax is distinct, as it shares only 30% of its gene products with its closest sequenced relatives. Remarkably, 34% of predicted genes over 500 nt in length were completely unique with no significant matches in the databases. As expected, Bacteriovorax shares several characteristic loci with the other delta-proteobacteria. A geneset shared between Bacteriovorax and Bdellovibrio that is not conserved among other delta-proteobacteria such as Myxobacteria (which destroy prey bacteria externally via lysis), or the non-predatory Desulfo-bacteria and Geobacter species was identified. These 291 gene orthologues common to both Bacteriovorax and Bdellovibrio may be the key indicators of host-interaction predatory-specific processes required for prey entry. The locus from Bdellovibrio bacteriovorus is implicated in the switch from predatory to prey/host-independent growth. Although the locus is conserved in B. marinus, the sequence has only limited similarity. The results of this study advance understanding of both the similarities and differences between Bdellovibrio and Bacteriovorax and confirm the distant relationship between the two and their separation into different families.
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影响因子：
3.2
作者：
Evans, Katy J.;Lambert, Carey;Sockett, R. Elizabeth
通讯作者：
Sockett, R. Elizabeth
DOI：
10.1099/ijs.0.02458-0
发表时间：
2004-07-01
影响因子：
2.8
作者：
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影响因子：
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影响因子：
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通讯作者：
Avison MB
影响因子：
3.7
作者：
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通讯作者：
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