Central prostaglandins in food intake regulation.

Central prostaglandins in food intake regulation.
复制标题

中枢前列腺素在食物摄入调节中的作用。

DOI:
10.1016/j.nut.2008.06.006
复制
发表时间:
2008
期刊:
影响因子:
4.4
通讯作者:
M. Yoshikawa
M. Yoshikawa
中科院分区:
医学3区
文献类型:
--
作者:
Kousaku Ohinata;M. Yoshikawa

文献摘要

参考文献

被引文献

相似文献

前列腺素E2(Prostaglandin,PG)和PGD2(prostaglandin,PGD2)是哺乳动物中枢神经系统中产生的一种激素,通过G蛋白偶联的七跨膜受体对睡眠、体温和疼痛反应具有多种中枢作用。我们发现,集中给药PGE 2通过EP 4受体抑制食物摄入,而PGD 2通过与神经肽Y Y1受体偶联的DP 1受体增加食物摄入。本文综述了中枢PGs在摄食调节中的作用,并讨论了PGs与控制摄食的神经肽的关系。
Prostaglandin (PG) E2and PGD2, produced in the mammalian central nervous system, are known to have a variety of central actions on sleep, body temperature, and pain response via G-protein–coupled seven-transmembrane receptors. We found that centrally administered PGE2suppressed food intake via the EP4receptor, whereas PGD2increased food intake via the DP1receptor coupled to the neuropeptide Y Y1receptor. In this review, we summarize roles of central PGs in food intake regulation and discuss the relation between PGs and neuropeptides controlling food intake.
DOI: 10.1093/sleep/12.1.13
发表时间: 1989-02-01
期刊: SLEEP
影响因子: 5.6
作者:
EVERSON, CA;BERGMANN, BM;RECHTSCHAFFEN, A
通讯作者: RECHTSCHAFFEN, A
DOI: 10.1093/sleep/28.10.1289
发表时间: 2005-10-01
期刊: SLEEP
影响因子: 5.6
作者:
Gangwisch, JE;Malaspina, D;Heymsfield, SB
通讯作者: Heymsfield, SB