Lupus Cohorts.

Lupus Cohorts.
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DOI:
10.1016/j.rdc.2021.04.009
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发表时间:
2021-08
期刊:
Rheumatic diseases clinics of North America
影响因子:
--
通讯作者:
Hasni SA
Hasni SA
中科院分区:
其他
文献类型:
--
作者:
Redmond C;Pamuk O;Hasni SA

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具有不同种族背景和异质临床特征的大型队列有助于了解狼疮的发病机制和自然史。他们提供了有关各种治疗方案的安全性和有效性的真实数据。有多个成熟的区域、国家和国际狼疮队列为我们对 SLE 的理解做出了重大贡献。使用社交媒体平台进行队列研究可以在相对较短的时间内显着增加研究系统性红斑狼疮等罕见疾病的范围。缺乏严格的纳入标准允许研究广泛的患者,但长期队列研究可能存在选择偏倚和不完整的数据。
Large cohorts with diverse ethnic backgrounds and heterogenous clinical features have been instrumental in understanding of pathogenesis and natural history of lupus. They have provided the real-life data about the safety and efficacy of various treatment regimens. There are multiple well established regional, national, and international lupus cohorts that have made significant contributions to our understanding of SLE. The use of social media platform for cohort-based studies can significantly increase the outreach in a relatively short time period for studying rare diseases such as SLE. Lack of strict inclusion criteria allows to study a broad range of patients but there is possibility of selection bias and incomplete data in long-term cohort studies.
DOI: 10.1002/acr.23925
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影响因子: 4.7
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