First-episode schizophrenia: II. Premorbid patterns by gender.
First-episode schizophrenia: II. Premorbid patterns by gender.
复制标题
首发精神分裂症：II。
作者：
T. Larsen;T. McGlashan;J. O. Johannessen;Lars Vibe
本文介绍了挪威的首发精神分裂症患者的病前适应量表的应用。该量表从几个方面衡量病前功能：在不同发展时期的功能，随着时间的推移功能的变化，以及随着时间的推移功能的独特模式。性别差异是惊人的，男性得分较差，恶化速度比女性，特别是接近发病。虽然男性未治疗精神病（DUP）的持续时间明显较长，但性别内DUP与病前功能之间的相关性在很大程度上不显著，发病前功能和发病年龄的分析也是如此。另一方面，我们重复了一些研究，这些研究发现了较差的病前功能与隐匿性发作和阴性症状之间的关联。总的来说，我们的发病前模式表明，一个无症状的发病前赤字形成的过程之前的一段时间，特别是男性。这些模式还表明，活跃的症状形成并不总是先于这种恶化的过程。
This article describes the application of the Premorbid Adjustment Scale to Norwegian subjects with first-episode schizophrenia. The scale measures premorbid functioning from several perspectives: functioning at different developmental periods, change of functioning over time, and distinctive patterns of functioning over time. Gender differences were striking, with males scoring poorer and deteriorating faster than females, especially closer to onset. While the duration of untreated psychosis (DUP) was significantly longer in males, correlations between DUP and premorbid functioning within gender were largely nonsignificant, as were the analyses of premorbid functioning and age at onset. On the other hand, we replicated studies that found associations between poorer premorbid functioning and insidious onset and negative symptoms. Overall, our premorbid patterns suggest that a process of asymptomatic premorbid deficit formation precedes onset by some period, especially among males. The patterns also suggest that active symptom formation does not always precede this deteriorative process.
DOI：
10.1176/ajp.145.5.578
发表时间：
1988-05
期刊：
The American journal of psychiatry
影响因子：
--
作者：
W. Carpenter;D. Heinrichs;A. Wagman
通讯作者：
W. Carpenter;D. Heinrichs;A. Wagman
DOI：
10.1176/ajp.147.3.290
发表时间：
1990-03
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Robert W. Buchanan;Brian Kirkpatrick;D. Heinrichs;William T. Carpenter
通讯作者：
Robert W. Buchanan;Brian Kirkpatrick;D. Heinrichs;William T. Carpenter
DOI：
10.1176/ajp.149.9.1183
发表时间：
1992-09
期刊：
The American journal of psychiatry
影响因子：
--
作者：
A. Loebel;J. Lieberman;J. Alvir;D. Mayerhoff;S. Geisler;Szymański
通讯作者：
A. Loebel;J. Lieberman;J. Alvir;D. Mayerhoff;S. Geisler;Szymański