Mesenchymal stem cells isolated from adipose and other tissues: basic biological properties and clinical applications.
Mesenchymal stem cells isolated from adipose and other tissues: basic biological properties and clinical applications.
复制标题
从脂肪和其他组织分离的间充质干细胞:基本的生物学特性和临床应用。
DOI:
10.1155/2012/461718
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发表时间:
2012
影响因子:
4.3
通讯作者:
Mizuno H
中科院分区:
文献类型:
--
作者:
Orbay H;Tobita M;Mizuno H
Mesenchymal stem cells (MSCs) are adult stem cells that were initially isolated from bone marrow. However, subsequent research has shown that other adult tissues also contain MSCs. MSCs originate from mesenchyme, which is embryonic tissue derived from the mesoderm. These cells actively proliferate, giving rise to new cells in some tissues, but remain quiescent in others. MSCs are capable of differentiating into multiple cell types including adipocytes, chondrocytes, osteocytes, and cardiomyocytes. Isolation and induction of these cells could provide a new therapeutic tool for replacing damaged or lost adult tissues. However, the biological properties and use of stem cells in a clinical setting must be well established before significant clinical benefits are obtained. This paper summarizes data on the biological properties of MSCs and discusses current and potential clinical applications.
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影响因子:
--
作者:
Choi, Eun Wha;Shin, Il Seob;Hong, Sung Hwa
通讯作者:
Hong, Sung Hwa
影响因子:
4.9
作者:
Djouad F;Bony C;Häupl T;Uzé G;Lahlou N;Louis-Plence P;Apparailly F;Canovas F;Rème T;Sany J;Jorgensen C;Noël D
通讯作者:
Noël D
DOI:
10.1111/j.1365-2184.1970.tb00347.x
发表时间:
1970-01-01
期刊:
CELL AND TISSUE KINETICS
影响因子:
--
作者:
FRIEDENSTEIN, AJ;CHAILAKHJAN, RK;LALYKINA, KS
通讯作者:
LALYKINA, KS
影响因子:
24.5
作者:
Duijvestein, Marjolijn;Vos, Anne Christine W.;Hommes, Daniel W.
通讯作者:
Hommes, Daniel W.
影响因子:
2.9
作者:
Asakura, A;Komaki, M;Rudnicki, MA
通讯作者:
Rudnicki, MA