Aerosol jet printing of surface acoustic wave microfluidic devices.
Aerosol jet printing of surface acoustic wave microfluidic devices.
复制标题
DOI：
10.1038/s41378-023-00606-z
复制
发表时间：
2024
影响因子：
7.9
通讯作者：
Huang, Tony Jun
中科院分区：
文献类型：
--
作者：
Rich, Joseph;Cole, Brian;Li, Teng;Lu, Brandon;Fu, Hanyu;Smith, Brittany N.;Xia, Jianping;Yang, Shujie;Zhong, Ruoyu;Doherty, James L.;Kaneko, Kanji;Suzuki, Hiroaki;Tian, Zhenhua;Franklin, Aaron D.;Huang, Tony Jun
由于其独特而强大的特性，包括高精度操作、多功能性、可集成性、生物相容性、非接触式和快速驱动，表面声波（SAW）技术在微流体中的应用大大推进了芯片实验室的应用。然而，SAW微流控器件的发展受到复杂且耗时的微/纳米制造技术以及多步光刻和真空处理的洁净室设施的限制。为了简化SAW微流控器件的尺寸和功能定制，我们采用了气溶胶喷射打印的增材制造技术。我们成功地制作了不同材料的定制SAW微流控器件，包括银纳米线、石墨烯和聚（3,4-乙烯二氧噻吩）聚苯乙烯磺酸盐（PEDOT:PSS）。为了表征和比较这些气溶胶射流打印SAW微流控器件与洁净室制造的同类器件的声驱动性能，通过扫描激光多普勒振动仪直接测量了不同制造器件的波位移和共振频率。最后，我们成功地进行了声流和颗粒浓度实验，以展示气溶胶射流打印设备在芯片实验室应用的能力。总的来说，我们展示了一种新颖的基于溶液的、直接写入的、单步的、无洁净室的增材制造技术，可以快速开发SAW微流体装置，在生物学、化学、工程和医学领域显示出应用的可行性。
The addition of surface acoustic wave (SAW) technologies to microfluidics has greatly advanced lab-on-a-chip applications due to their unique and powerful attributes, including high-precision manipulation, versatility, integrability, biocompatibility, contactless nature, and rapid actuation. However, the development of SAW microfluidic devices is limited by complex and time-consuming micro/nanofabrication techniques and access to cleanroom facilities for multistep photolithography and vacuum-based processing. To simplify the fabrication of SAW microfluidic devices with customizable dimensions and functions, we utilized the additive manufacturing technique of aerosol jet printing. We successfully fabricated customized SAW microfluidic devices of varying materials, including silver nanowires, graphene, and poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS). To characterize and compare the acoustic actuation performance of these aerosol jet printed SAW microfluidic devices with their cleanroom-fabricated counterparts, the wave displacements and resonant frequencies of the different fabricated devices were directly measured through scanning laser Doppler vibrometry. Finally, to exhibit the capability of the aerosol jet printed devices for lab-on-a-chip applications, we successfully conducted acoustic streaming and particle concentration experiments. Overall, we demonstrated a novel solution-based, direct-write, single-step, cleanroom-free additive manufacturing technique to rapidly develop SAW microfluidic devices that shows viability for applications in the fields of biology, chemistry, engineering, and medicine.
登录
查看更多内容
声表面波微流控边界驱动流动的三维数值模拟与实验研究
影响因子：
6.1
作者：
Chen C;Zhang SP;Mao Z;Nama N;Gu Y;Huang PH;Jing Y;Guo X;Costanzo F;Huang TJ
通讯作者：
Huang TJ
影响因子：
44.1
作者：
Friend, James;Yeo, Leslie Y.
通讯作者：
Yeo, Leslie Y.
DOI：
10.1073/pnas.1413325111
发表时间：
2014-09-09
影响因子：
11.1
作者：
Ding, Xiaoyun;Peng, Zhangli;Huang, Tony Jun
通讯作者：
Huang, Tony Jun
影响因子：
6.1
作者：
Franke, T.;Braunmueller, S.;Weitz, D. A.
通讯作者：
Weitz, D. A.
影响因子：
7.9
作者：
Fan, Yanping;Wang, Xuan;Ren, Jiaqi;Lin, Francis;Wu, Jiandong
通讯作者：
Wu, Jiandong