Recent advances in acoustofluidic separation technology in biology.

Recent advances in acoustofluidic separation technology in biology.
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DOI:
10.1038/s41378-022-00435-6
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发表时间:
2022
影响因子:
7.9
通讯作者:
Wu, Jiandong
Wu, Jiandong
中科院分区:
工程技术1区
文献类型:
--
作者:
Fan, Yanping;Wang, Xuan;Ren, Jiaqi;Lin, Francis;Wu, Jiandong

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Acoustofluidic separation of cells and particles is an emerging technology that integrates acoustics and microfluidics. In the last decade, this technology has attracted significant attention due to its biocompatible, contactless, and label-free nature. It has been widely validated in the separation of cells and submicron bioparticles and shows great potential in different biological and biomedical applications. This review first introduces the theories and mechanisms of acoustofluidic separation. Then, various applications of this technology in the separation of biological particles such as cells, viruses, biomolecules, and exosomes are summarized. Finally, we discuss the challenges and future prospects of this field.
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