Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism.
Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism.
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与白色脂肪褐变相关的因素：脂代谢的新调节剂。
DOI：
10.3390/ijms23147641
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发表时间：
2022-07-11
影响因子：
5.6
通讯作者：
中科院分区：
文献类型：
--
作者：
哺乳动物脂肪组织可根据其颜色、位置和细胞结构分为白色和棕色脂肪组织。某些条件，如交感神经兴奋，可以诱导白色脂肪细胞成为一种新的脂肪细胞类型，称为米色脂肪细胞。导致白色脂肪细胞转化为米色脂肪细胞的过程称为白色脂肪布朗宁。白色和米色脂肪细胞之间的动态平衡与身体的代谢稳态密切相关。研究白色脂肪布朗宁的信号转导途径，可能为肥胖症的治疗和缓解肥胖相关的糖脂代谢紊乱提供新的思路。本文综述了近年来白色脂肪布朗宁的研究进展以及BAT在脂肪代谢中的作用。
Mammalian adipose tissue can be divided into white and brown adipose tissue based on its colour, location, and cellular structure. Certain conditions, such as sympathetic nerve excitement, can induce the white adipose adipocytes into a new type of adipocytes, known as beige adipocytes. The process, leading to the conversion of white adipocytes into beige adipocytes, is called white fat browning. The dynamic balance between white and beige adipocytes is closely related to the body’s metabolic homeostasis. Studying the signal transduction pathways of the white fat browning might provide novel ideas for the treatment of obesity and alleviation of obesity-related glucose and lipid metabolism disorders. This article aimed to provide an overview of recent advances in understanding white fat browning and the role of BAT in lipid metabolism.
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影响因子：
7.3
作者：
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通讯作者：
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影响因子：
7.9
作者：
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通讯作者：
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影响因子：
4.4
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通讯作者：
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影响因子：
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作者：
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通讯作者：
Collins, S
影响因子：
8.8
作者：
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通讯作者：
Bottini, Ruben