Genetic and cell biological analysis of calpain: a potential therapeutic target in breast cancer

钙蛋白酶的遗传和细胞生物学分析：乳腺癌的潜在治疗靶点

• 批准号: 199635
• 负责人: Greer Peter A
• 金额: $ 53.52万
• 依托单位: Queen's University (Kingston, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-03-01 至 2015-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=199635&lang=en
• 关键词: Apoptosis; Calpain; Cancer; Her2 / Neu; Transgenic / Knockout Mice; Trastuzumab

In order for cancer to evolve, grow and spread, the transformed cancer cells must evade the normal safeguards that usually cause programmed cell death of transformed cells. Then they must acquire the ability to enter the vascular system, travel to distan

为了使癌症进化、生长和扩散，转化的癌细胞必须逃避通常导致转化细胞程序性细胞死亡的正常保护措施。 然后他们必须获得进入血管系统的能力，