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Understanding the mechanism behind V-ATPase mutations leading to Osteopetrosis, Distal Renal Tubule Acidosis and Cutis Laxa through study of yeast V-ATPase expression and activity.

Understanding the mechanism behind V-ATPase mutations leading to Osteopetrosis, Distal Renal Tubule Acidosis and Cutis Laxa through study of yeast V-ATPase expression and activity.
通过研究酵母 V-ATP 酶表达和活性,了解导致骨石症、远端肾小管酸中毒和皮肤松弛的 V-ATP 酶突变背后的机制。
批准号:
205367
负责人:
Tan Albert L
金额:
$0.36万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2010
资助国家:
加拿大
项目状态:
已结题
起止时间:
2010-03-01 至 2010-06-01

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英文摘要
V-ATPase is an evolutionarily conserved enzyme required for acidifying urine, aiding normal physiological bone break down, and maintaining skin elasticity. V-ATPase consists of many subunits, that together, make up the functioning enzyme. One of these sub
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