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Diabetes and the mechanism(s) of renal tubular apoptosis in db/db mouse kidneys

Diabetes and the mechanism(s) of renal tubular apoptosis in db/db mouse kidneys
糖尿病和 db/db 小鼠肾脏肾小管凋亡的机制
批准号：
202359
负责人：
Chan John S
金额：
$44.19万
依托单位：
Centre hospitalier de l'Universit de Montral (CHUM)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-03-01 至 2015-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=202359&lang=en
关键词：
Albumin Angiotensinogen Caspase-12 Gene Expression Diabetic Nephropathy Molecular And Cell Biology Oxidative Stress Renal Proximal Tubular Cells Renin-Angiotensin System Transgenic Mice Tubular Apoptosis And Atrophy

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Diabetic nephropathy (DN) is a major cause of morbidity and mortality in both type 1 and type 2 diabetics. It is estimated that approximately 30-50% of diabetic patients in Canada and in the USA will eventually develop chronic renal failure (or end-stage
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