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Reactive Oxygen Species, Bcl-2-Modifying Factor and Tubular Atrophy in Diabetic Kidneys

Reactive Oxygen Species, Bcl-2-Modifying Factor and Tubular Atrophy in Diabetic Kidneys
糖尿病肾中的活性氧、Bcl-2 修饰因子和肾小管萎缩
批准号：
252494
负责人：
Chan John S
金额：
$50.07万
依托单位：
Centre hospitalier de l'Universit de Montral (CHUM)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-03-01 至 2017-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252494&lang=en
关键词：
Bcl-2-Modifying Factor Diabetic Nephropathy Glucose Signaling Insulin Signaling Kidney Molecular Biology Oxidative Stress Physiology Renin-Angiotensin System Transgenic And Knockout Mice

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英文摘要
Diabetic nephropathy (DN) is a major cause of morbidity and mortality in patients with diabetes. It is estimated that approximately 30-50% of the diabetic patients in Canada and in the USA will eventually develop DN leading to chronic renal failure (or e
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