A randomized trial to compare effectiveness of 4 months Rifampin (4 RIF) with 9 months Isoniazid (9 INH) in the prevention of active TB in children: The P4v9 Trial

一项比较 4 个月利福平 (4 RIF) 与 9 个月异烟肼 (9 INH) 预防儿童活动性结核病有效性的随机试验：P4v9 试验

• 批准号: 210714
• 负责人: Menzies Richard
• 金额: $ 74.57万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-09-01 至 2015-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=210714&lang=en
• 关键词: Child Health; Global Health; Latent Tb Infection; Randomized Trail; Tuberculosis Prevention; Tuberculosis Treatment

Tuberculosis (TB) is spread by airborne transmission from adults with active contagious TB to children, especially those living in the same household. Once children are exposed and infected they are at very high risk to develop active TB - which can be le

结核病(TB)通过空气传播，从患有活动性传染性结核病的成年人传播给儿童，特别是那些生活在同一家庭的儿童。一旦儿童暴露并受到感染，他们患活动性肺结核的风险很高，而活动性肺结核的风险可能很小。