Point of Care Technologies for Nutrition, Infection, and Cancer for Global Health (PORTENT)
全球健康营养、感染和癌症护理点技术 (PORTENT)
基本信息
- 批准号:10714506
- 负责人:
- 金额:$ 160.64万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-09-13 至 2028-07-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAfricaAnemiaAreaAsiaBiological SciencesBusinessesCOVID-19 pandemicCapitalCervical Cancer ScreeningClinicalCommunicable DiseasesConsensusDevelopmentDevice or Instrument DevelopmentDevicesDiagnosticDiagnostic testsDirect CostsDisparateEcologyEcuadorEducational workshopElementsEngineeringEntrepreneurshipEventFundingGenerationsHIVHealth PersonnelHealthcare SystemsHumanIncubatorsIndiaIndustrializationInfectionInfrastructureInstitutionInternationalIronKnowledgeLeadershipLettersLow incomeMalariaMalignant NeoplasmsMarketingMindModelingNeeds AssessmentNetwork-basedNew York CityNongovernmental OrganizationsNorth AmericaPatientsPersonsPoint of Care TechnologyPopulationPopulation HeterogeneityPositioning AttributePrimary CarePrimary Health CareQualifyingRegulatory AffairsReportingRotationSexually Transmitted DiseasesSiteSouth AmericaSystemTechnologyTestingTherapeuticTrainingTranslationsTravelUgandaUnited StatesUnited States National Institutes of HealthUniversitiesValidationVeteransclinical research sitecollegecommercializationdiagnostic technologiesearly screeningexperienceglobal healthhealth care disparityinterestlow and middle-income countriesmarginalizationmarginalized populationmultiplex detectionnext generationnutritionpoint of carepoint-of-care diagnosticsprogramsresearch and developmentscreeningstatisticstechnology developmenttechnology validationtraining opportunity
项目摘要
1.0 Overall Abstract
We propose the establishment of PORTENT – “Point-of-Care Technologies for Nutrition, Infection and Cancer
for Global Health” centered at Cornell University in partnership with Columbia and McGill Universities.
The recent Lancet Diagnostic Commission report states that the “diagnostic gap is most severe at the level of primary
health care, in which only about 19% of populations in low-income and lower-middle-income countries have
access to the simplest of diagnostic tests … People who are poor, marginalized, young, or less educated have the
least access to diagnostics.” Developing PoC devices for these populations is challenging. The needs are unique,
the users have disparate qualifications, the path to commercialization is different, the settings have variable
infrastructure, the regulatory agencies have distinctive requirements, and the stakeholders are diverse. The
PORTENT Center is unique as it (1) focuses on primary health care globally; (2) addresses the needs of the
most vulnerable in the US and internationally; and (3) enables a broad range of diagnostic technologies to be
validated on a global scale while simultaneously developing expertise and building capacity internationally
to have the most impact even beyond the center. The center builds on our decades of international experience in
validation, deployment, and commercialization of POC systems and incorporates clinical validation and satellite
technology sites across four continents enabling testing on diverse populations and with a unique set of users.
Our approach is fundamentally enabled by 5 key differentiable elements: (1) A rigorous approach to Needs
Assessment through the establishment of an annual Global PoC Needs Assessment Consensus developed by a
Needs Assessment Advisory Board; (2) The ability to validate PoC technologies on an exceptionally broad range
of established populations and biospecimens in New York City, Ecuador, India, and Uganda; (3) The
establishment of a “Lab-to-Market accelerator for Global Health Point of Care Technologies” to provide
commercialization and tech-to-market support for PORTENT projects; (4) Unique training opportunities and
knowledge transfer workshops for healthcare workers in LMICs on the use of PoC devices and clinical rotations
at our international sites for PoC developers; (5) Access to the team’s network of industrial partners, diagnostics
companies, regulatory experts, venture capital groups, and domestic & international non-governmental
organizations. Illustrative of what we will fund through PORTENT, we describe four “Year 1” projects that (1) enable
early screening of cervical cancer, (2) determination of iron status enabling anemia screening, (3) combined HIV and
multiplexed detection of sexually transmitted diseases, and (4) broader, cheaper, and more accurate malaria testing.
By the end of year 5, PORTENT will: initiate 20 independent PoC technology projects (with 30% from outside
US), engage ~ 15 teams in the Global Health Lab-to-Market accelerator program, train 30 health care workers
from LMICs on use of PoC technologies, and provide >20 clinical rotations for technology developers.
1.0总体摘要
项目成果
期刊论文数量(0)
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David Carl Erickson其他文献
David Carl Erickson的其他文献
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{{ truncateString('David Carl Erickson', 18)}}的其他基金
Point of Care Technologies for Nutrition, Infection, and Cancer for Global Health (PORTENT)
全球健康营养、感染和癌症护理点技术 (PORTENT)
- 批准号:
10714507 - 财政年份:2023
- 资助金额:
$ 160.64万 - 项目类别:
Artificial Intelligence and Precision Nutrition Training Program
人工智能与精准营养培训项目
- 批准号:
10752485 - 财政年份:2023
- 资助金额:
$ 160.64万 - 项目类别:
Paper-COVID - Platform for High-throughput SARS-CoV-2 Screening and Contact Tracing
Paper-COVID - 高通量 SARS-CoV-2 筛查和接触者追踪平台
- 批准号:
10196383 - 财政年份:2021
- 资助金额:
$ 160.64万 - 项目类别:
Development of a Point of Care Multiplexed Diagnostic Platform to Target Anemia and Micronutrient Deficiencies
开发针对贫血和微量营养素缺乏症的护理多重诊断平台
- 批准号:
9542788 - 财政年份:2017
- 资助金额:
$ 160.64万 - 项目类别:
Early Stage Diagnosis of Kaposi's Sarcoma in Limited Resource Settings using KS-Detect
使用 KS-Detect 在有限资源环境下对卡波西肉瘤进行早期诊断
- 批准号:
9334145 - 财政年份:2016
- 资助金额:
$ 160.64万 - 项目类别:
FeverPhone: Point of Care Diagnosis of Acute Febrile Illness using a Mobile Device
FeverPhone:使用移动设备对急性发热性疾病进行护理点诊断
- 批准号:
9008392 - 财政年份:2016
- 资助金额:
$ 160.64万 - 项目类别:
Early Stage Diagnosis of Kaposi's Sarcoma in Limited Resource Settings using KS-Detect
使用 KS-Detect 在有限资源环境中对卡波西肉瘤进行早期诊断
- 批准号:
9031275 - 财政年份:2016
- 资助金额:
$ 160.64万 - 项目类别:
Early Stage Diagnosis of Kaposi's Sarcoma in Limited Resource Settings using KS-Detect
使用 KS-Detect 在有限资源环境下对卡波西肉瘤进行早期诊断
- 批准号:
10018466 - 财政年份:2016
- 资助金额:
$ 160.64万 - 项目类别:
FeverPhone: Point of Care Diagnosis of Acute Febrile Illness using a Mobile Device
FeverPhone:使用移动设备对急性发热性疾病进行护理点诊断
- 批准号:
9301546 - 财政年份:2016
- 资助金额:
$ 160.64万 - 项目类别:
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