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Novel mechanisms underlying ciliogenesis, planar cell polarity, and polycystic kidney disease

Novel mechanisms underlying ciliogenesis, planar cell polarity, and polycystic kidney disease
纤毛发生、平面细胞极性和多囊肾病的新机制
批准号：
210702
负责人：
Ciruna Brian G
金额：
$65.19万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-09-01 至 2015-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=210702&lang=en
关键词：
Cell Biology Cell Polarity Ciliogenesis Developmental Genetics Embryonic Morphogenesis Experimental Embryology Live Imaging Polycystic Kidney Disease Zebrafish

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英文摘要
Polycystic kidney disease (PKD) is the most common life-threatening syndrome that can be inherited from generation through generation. It afflicts approximately 1 in 500 people, and 50% of these individuals will ultimately lose all kidney function. Treatm
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