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Taking the "idiopathic" out of scoliosis: from biology and genetics to non-invasive therapies

Taking the "idiopathic" out of scoliosis: from biology and genetics to non-invasive therapies
消除脊柱侧凸的“特发性”：从生物学和遗传学到非侵入性治疗
批准号：
388548
负责人：
Ciruna Brian G
金额：
$258.02万
依托单位：
Hospital for Sick Children (Toronto)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2018
资助国家：
加拿大
项目状态：
未结题
起止时间：
2018-09-01 至 2025-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=388548&lang=en
关键词：
Cerebrospinal Fluid Csf-Contacting Neurons Developmental Genetics Idiopathic Scoliosis Motile Cilia Neuroinflammation Pre-Clinical Models Small Molecule Screens Whole Genome Sequencing Zebrafish Models Of Human Disease

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中文摘要
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英文摘要
Idiopathic scoliosis (AIS) is a poorly understood disorder characterized by rotational spine deformity that typically arises during adolescence in otherwise healthy individuals. AIS afflicts 4% of children worldwide and in severe cases (predominantly fema
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The 17th International Zebrafish Conference: To be held for the first time in Canada, at the beautiful Centre Mont-Royal in the heart of Montreal, Quebec, from June 22-26 2022.
  • 批准号：
    460710
  • 项目类别：
    Miscellaneous Programs
  • 资助金额：
    $0.73万
  • 财政年份：
    2022
  • 负责人：
    Ciruna Brian G
  • 依托单位：
    Centre Mont-Royal (Montral, Qubec)
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    384863
  • 项目类别：
  • 资助金额：
    $101.99万
  • 财政年份：
    2017
  • 负责人：
    Ciruna Brian G
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Applying unique zebrafish models to elucidate and functionally validate the molecular genetic causes of adolescent idiopathic scoliosis
  • 批准号：
    342981
  • 项目类别：
    Operating Grants
  • 资助金额：
    $66.28万
  • 财政年份：
    2016
  • 负责人：
    Ciruna Brian G
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  • 批准号：
    320405
  • 项目类别：
    Operating Grants
  • 资助金额：
    $56.78万
  • 财政年份：
    2015
  • 负责人：
    Ciruna Brian G
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