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Applying unique zebrafish models to elucidate and functionally validate the molecular genetic causes of adolescent idiopathic scoliosis

Applying unique zebrafish models to elucidate and functionally validate the molecular genetic causes of adolescent idiopathic scoliosis
应用独特的斑马鱼模型阐明和功能验证青少年特发性脊柱侧凸的分子遗传原因
批准号:
342981
负责人:
Ciruna Brian G
金额:
$66.28万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-03-01 至 2021-03-01

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中文摘要
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英文摘要
Idiopathic scoliosis (IS) is a complex genetic disorder characterized by three-dimensional spinal curvatures that typically arise during adolescence in otherwise healthy individuals. IS afflicts 3% of children worldwide and, in severe cases, can produce c
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The 17th International Zebrafish Conference: To be held for the first time in Canada, at the beautiful Centre Mont-Royal in the heart of Montreal, Quebec, from June 22-26 2022.
  • 批准号:
    460710
  • 项目类别:
    Miscellaneous Programs
  • 资助金额:
    $0.73万
  • 财政年份:
    2022
  • 负责人:
    Ciruna Brian G
  • 依托单位:
Taking the "idiopathic" out of scoliosis: from biology and genetics to non-invasive therapies
  • 批准号:
    388548
  • 项目类别:
    Operating Grants
  • 资助金额:
    $258.02万
  • 财政年份:
    2018
  • 负责人:
    Ciruna Brian G
  • 依托单位:
Canada Research Chair - Tier 1 - CIHR Funded
  • 批准号:
    384863
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2017
  • 负责人:
    Ciruna Brian G
  • 依托单位:
Novel mechanisms underlying ciliogenesis, planar cell polarity and cystic kidney disease
  • 批准号:
    320405
  • 项目类别:
    Operating Grants
  • 资助金额:
    $56.78万
  • 财政年份:
    2015
  • 负责人:
    Ciruna Brian G
  • 依托单位:
海外基金