Inhibition of autophagy by the pRb tumor suppressor
Inhibition of autophagy by the pRb tumor suppressor
批准号:
171208
负责人:
Zacksenhaus Eldad
金额:
$35.6万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-09-01 至 2012-09-01
中文摘要
点击翻译按钮获取中文摘要
英文摘要
The tumor suppressor pRb is lost by mutations or functional inactivation in most, if not all, human cancers. The prevailing view is pRb controls cell proliferation and survival as well as differentiation (i.e. by stimulating the differentiation program).
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Prevention of metastatic triple negative breast cancer (TNBC) by targeting shared- and metastasis-enriched oncogenic pathways
-
批准号:494896
-
项目类别:Operating Grants
-
资助金额:$7.29万
-
财政年份:2023
-
负责人:Zacksenhaus Eldad
-
依托单位:
New mouse models and targeted therapies for aggressive forms of germline and sporadic pineoblastoma
-
批准号:443784
-
项目类别:Operating Grants
-
资助金额:$69.66万
-
财政年份:2021
-
负责人:Zacksenhaus Eldad
-
依托单位:
Mechanisms of diabetes and aging in constitutively active, phosphorylation-resistant pRb knockin mice
-
批准号:450441
-
项目类别:Operating Grants
-
资助金额:$1.21万
-
财政年份:2021
-
负责人:Zacksenhaus Eldad
-
依托单位:
Mechanisms of diabetes and aging in constitutively active, phosphorylation-resistant pRb knockin mice
-
批准号:443790
-
项目类别:Operating Grants
-
资助金额:$58.24万
-
财政年份:2021
-
负责人:Zacksenhaus Eldad
-
依托单位:
A model for Group C Medulloblastoma induced by deletion of RB1 and p53 tumor suppressors
-
批准号:290822
-
项目类别:Operating Grants
-
资助金额:$35.47万
-
财政年份:2013
-
负责人:Zacksenhaus Eldad
-
依托单位:
国内基金
海外基金
中国北方人群肺癌患者Cancer/Testis抗原表达谱绘制表位鉴定及功能性抗原特异性CTL制备研究
-
批准号:81673007
-
项目类别:面上项目
-
资助金额:54.0万元
-
批准年份:2016
-
负责人:金时
-
依托单位: