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New mouse models and targeted therapies for aggressive forms of germline and sporadic pineoblastoma

New mouse models and targeted therapies for aggressive forms of germline and sporadic pineoblastoma
针对侵袭性种系和散发性松果体母细胞瘤的新小鼠模型和靶向治疗
批准号:
443784
负责人:
Zacksenhaus Eldad
金额:
$69.66万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-04-01 至 2026-04-01

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中文摘要
翻译
松果体母细胞瘤(PB),一种松果体癌,是一种罕见但致命的脑肿瘤,影响非常小的男孩和女孩。治疗这种疾病的一个主要问题是缺乏小鼠模型和在培养中培养人PB细胞的困难。一个博士
英文摘要
Pineoblastoma (PB), a cancer of the pineal gland, is a rare but lethal brain tumor affecting very young boys and girls. A major problem in tackling this disease is the absence of mouse models and the difficulty in growing human PB cells in culture. Dr. A
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海外基金