Regulation of Vertebrate Planar Cell Polarity (PCP)

脊椎动物平面细胞极性 (PCP) 的调节

• 批准号: 184448
• 负责人: Hayes Madeline
• 金额: $ 7.65万
• 依托单位: Hospital for Sick Children (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-10-01 至 2011-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=184448&lang=en
• 关键词: Cell Migration; Embyrogenesis; Genetics; Live Imaging; Microinjection (Dna; Neurulation; Planar Cell Polarity; Rna); Signal Transduction; Subcellular Protein Localisation; Tissue Dynamics

Cell polarity is essential for proper cellular and tissue function. In addition to polarization across the apical-basal cell axis, cells frequently polarize across the plane or field of a tissue. In vertebrates, this planar cell polarity (or PCP) is an im

细胞极性对于正常的细胞和组织功能至关重要。除了跨越顶基细胞轴的极化之外，细胞还经常跨越组织的平面或区域极化。在脊椎动物中，这种平面细胞极性（或PCP）是一种免疫系统，