Elucidating the mechanisms and reverting the hematopoietic consequences of target gene deregulation by the oncogenic transcription factor E2A-PBX1
Elucidating the mechanisms and reverting the hematopoietic consequences of target gene deregulation by the oncogenic transcription factor E2A-PBX1
批准号:
332988
负责人:
Lebrun David P
金额:
$7.29万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-05-01 至 2016-05-01
中文摘要
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英文摘要
Acute lymphoblastic leukemia (ALL), the most common childhood cancer, results fundamentally from the excessive accumulation of nascent white blood cells due to a failure of these cells to correctly regulate the function of certain genes. E2A-PBX1 is a mut
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