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Immune responses to drugs that cause idiosyncratic liver injury and agranulocytosis

Immune responses to drugs that cause idiosyncratic liver injury and agranulocytosis
对引起特异质肝损伤和粒细胞缺乏症的药物的免疫反应
批准号:
320828
负责人:
Uetrecht Jack P
金额:
$36.16万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-03-01 至 2020-03-01

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中文摘要
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英文摘要
Many drugs can cause unexpected or idiosyncratic serious side effects or adverse reactions. In many cases these adverse reactions are mediated by the immune system, i.e. they are "allergic" in nature. These adverse effects can lead to liver failure or l
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Study of the Innate Immune Response to Drugs that Cause IDRs
  • 批准号:
    444245
  • 项目类别:
    Operating Grants
  • 资助金额:
    $50.16万
  • 财政年份:
    2021
  • 负责人:
    Uetrecht Jack P
  • 依托单位:
Investigation of the Mechanisms of Idiosyncratic Drug Reactions
  • 批准号:
    252374
  • 项目类别:
    Operating Grants
  • 资助金额:
    $38.04万
  • 财政年份:
    2012
  • 负责人:
    Uetrecht Jack P
  • 依托单位:
Macrophage Activation by Drugs Leading to Autoimmunity
  • 批准号:
    170793
  • 项目类别:
    Operating Grants
  • 资助金额:
    $38.82万
  • 财政年份:
    2008
  • 负责人:
    Uetrecht Jack P
  • 依托单位:
海外基金