2023 Drug Metabolism Gordon Research Conference and Gordon Research Seminar

2023年药物代谢戈登研究会议暨戈登研究研讨会

• 批准号: 10751553
• 负责人: Jane Kenny
• 金额: $ 2.8万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-06 至 2024-07-05
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10751553
• 关键词: Automobile Driving; Career Choice; Case Study; Clinical; Collaborations; Data; Discipline; Dose; Emerging Technologies; Environment; Exposure to; Future; Geographic Locations; Growth; Hour; In Vitro; Industry; Learning; Medicine; Mentors; Mentorship; Metabolism; Modality; Oral; Outcome; Patients; Pharmaceutical Preparations; Pharmacotherapy; Problem Solving; Process; Property; Recording of previous events; Recreation; Research; Research Personnel; Safety; Science; Scientist; Students; Techniques; Therapeutic; Thinking; Time; Translations; Underrepresented Minority; Universities; Woman; Work; absorption; career; clinical predictors; collaborative environment; design; drug development; drug discovery; drug metabolism; gender diversity; improved; in silico; in vivo; lectures; meetings; models and simulation; novel; novel strategies; posters; pre-clinical; programs; symposium; tool; translational model

Abstract The field of Drug Metabolism is focused on defining and mechanistically understanding the Absorption, Distribution, Metabolism and Elimination (ADME) properties of a molecule. ADME has a tremendous influence on efficacy, safety, and dosing of therapeutic molecules and novel modalities, beyond small and large molecules, are amongst the medicines of today and tomorrow. The 51st Drug Metabolism GRC will focus on the challenges and opportunities of the next 50 years of ADME science. Emphasis will be on cutting-edge science and the importance of interconnectedness among ADME disciplines so that we fully tap into the potential of emerging technologies and novel approaches in discovering, developing, and safely using medicine from diverse modalities. The conference will bring together academic, industry and regulatory scientists at all career stages and provide a stimulating and collaborative environment to discuss unpublished research and learn about the ADME challenges of diverse modalities. The informal venue of the Drug Metabolism GRC provides an ideal environment to establish this. This conference will provide a forum for early career scientists to expand their scientific breadth, interact with leaders in the field, establish future collaborative relationships, and consider various career paths. A Gordon Research Seminar will precede the main GRC conference, providing a unique environment for students and early career researchers to present their work, connect and have access to mentoring. Attendees will be exposed to cutting edge presentations by world-class speakers to stimulate new ideas and collaborations with focus on diversity and connectivity driving translational ADME science so that new treatments and cures can be delivered to patients faster. The lectures are held in the mornings and evenings over 4.5 days with the afternoons available for informal discussions and recreation. GRC meetings are small and designed for more discussion time during both the formal scientific sessions and during informal interactions (e.g., poster sessions, mealtimes, afternoon outings). To facilitate ample opportunity to discuss their work, the Drug Metabolism GRC organizes four, two-hour poster sessions, with each poster presenter (at least 60) available for discussion during two sessions.

抽象的 药物代谢领域的重点是定义和机械地理解吸收， 分子的分布、代谢和消除 (ADME) 特性。 ADME 拥有巨大的 对治疗分子和新模式的功效、安全性和剂量的影响超出了小范围 和大分子，是今天和明天的药物之一。第51届药物代谢 GRC将重点关注ADME科学未来50年的挑战和机遇。强调 将讨论尖端科学以及 ADME 学科之间相互关联的重要性，以便 我们充分利用新兴技术和新方法的潜力来发现、 开发并安全地使用多种方式的药物。会议将汇聚 各个职业阶段的学术、工业和监管科学家，并提供激励和 协作环境来讨论未发表的研究并了解 ADME 的挑战 形式多样。药物代谢 GRC 的非正式场所为 建立这个。这次会议将为早期职业科学家提供一个扩大其科学领域的论坛 广度，与该领域的领导者互动，建立未来的合作关系，并考虑 各种职业道路。戈登研究研讨会将在 GRC 主要会议之前举行，提供 为学生和早期职业研究人员展示他们的工作、联系和交流的独特环境 获得指导。与会者将有机会聆听世界级演讲者的前沿演讲 激发新的想法和合作，重点关注多样性和连通性，推动转化 ADME 科学可以更快地为患者提供新的治疗方法和治愈方法。讲座内容为 为期 4.5 天的上午和晚上举行，下午可进行非正式讨论 和休闲。 GRC 会议规模较小，旨在在正式会议期间有更多讨论时间 科学会议和非正式互动期间（例如海报会议、进餐时间、下午郊游）。 为了提供充足的机会讨论他们的工作，药物代谢 GRC 组织了四次两小时的会议 海报会议，每位海报展示者（至少 60 名）可在两次会议期间进行讨论。